A new paper from the lab of Whitehead Institute Director Ruth Lehmann reveals how primordial germ cells in flies migrate from one end of an embryo to the other during development. The work could have implications for how scientists study germ cells in vivo, as well as other motile cells such as cancer cells.
Researchers at Whitehead Institute uncover the 3-D structure of GATOR2, a protein complex that plays a critical role in a signaling pathway that regulates cell growth.
Whitehead Institute researchers find a role for condensates, droplets involved in corralling proteins inside of cells, in disease. They provide a catalog of disease-causing mutations that likely affect condensates as a resource for future research.
Learn about a molecule that can take the place of oxygen in the electron transport chain; a key protein that helps sea star embryos establish polarity early in development; and a new approach to cataloguing cells' many DNA repair mechanisms. Our latest research highlights video features work from the labs of Iain Cheeseman and Jonathan Weissman.
New research from Whitehead Institute Member Jonathan Weissman and collaborators enables researchers to predict a cell’s path over time, such as what type of cell it will become, in normal settings or under genetic perturbations.
Learn about the role of swarm cells in ovarian development; the single-step fate model in planarian neoblasts; and a new gene-editing technique, CRISPRoff. Our latest research highlights video features work from the labs of Ruth Lehmann, Peter Reddien and Jonathan Weissman.
Ann Boija is a senior researcher in Whitehead Institute Member Richard (Rick) Young’s lab studying the role of cellular structures called condensates in gene regulation. We sat down with Boija to learn more about her and her experiences in and out of the lab.
