Technology and methods

Whitehead Institute Member David Bartel and colleagues uncovered how small changes in the molecular machines that carry out RNA interference can lead to big differences in the efficacy of gene silencing. Their findings have implications for the design of gene-silencing therapeutics.

From how genes are regulated, to how cells transport important cargo — there are many biological processes that work similarly across organisms, and are versatile in their function. Click here to watch a video on how Whitehead Institute researchers are finding ways to tailor existing biological processes to expand the potential to address complex problems.