Core Facilities

The cores, staffed by experts and providing state-of-the-art instrumentation and tools, allow our scientists to pursue more ambitious investigations. Our core facilities scientists are instrumental in pushing the boundaries of current research methods, tailoring techniques to the scientific question at hand.
BaRC develops computational strategies and techniques that let researchers tackle big datasets and assists in creating graphics for publications. Tools developed and maintained by BaRC include TargetScan, one of the most widely used tools for predicting microRNA targets.
The Genome Technology Core stays on the cutting edge of the always-developing genomics field. The core offers single cell sequencing, next-generation sequencing on the Illumina platform, real-time PCR, and more.
The Functional Genomics Platform specializes in adapting CRISPR screens to new research needs, assisting researchers at all stages of the screening process, from experimental design to data analysis and follow-up strategies.
The Metabolite Profiling Core Facility allows researchers to explore the diverse world of small molecules and metabolites with high-resolution instruments. The core provides liquid chromatography mass spectrometry (LCMS) and assists in project design, implementation, and analysis.
The Proteomics Core performs “bottom-up” proteomics techniques that involve digesting proteins and analyzing their component peptides with high resolution mass spectrometry. The core offers quantitative proteomics, identification of post-translational protein modifications, and more.
The W.M. Keck Imaging Facility provides researchers with state-of-the-art instrumentation and technical expertise, assists investigators in applying sophisticated microscopy techniques, and trains researchers in microscopy techniques and methodology.

Len Rubenstein/Whitehead Institute
Glasswashing Core Facility
Whitehead Institute Greenhouse
Human Stem Cell Facility