Protein form and function

New, reversible CRISPR method can control gene expression while leaving underlying DNA sequence unchanged

If we imagine the cell as an orchestra, with many musicians who each have a small part to play, then what conducts all of these musicians and keeps them organized and harmonized as they play a symphony?

Founding Member Harvey Lodish has been twice honored by the international science community for his path-breaking scientific accomplishments and intellectual leadership.

New research from the lab of Whitehead Institute Member Richard Young suggests that the products of transcription — RNA molecules — regulate their own production through a feedback loop

A proposed project would provide a way to store carbon indefinitely in the tissues of specially engineered plants.

Whitehead Institute Member David Sabatini’s latest in a series of tools to isolate and analyze the contents of specific organelles helps researchers study melanosomes, the structures inside of cells responsible for skin color.

Tiny microRNAs help destroy unwanted messenger RNAs in cells. Here’s how the body keeps them in check.

A new experimental system shows how insulin-producing beta cells react under autoimmune attack during type 1 diabetes; the results could lead to better treatments.

Whitehead Institute Member Sebastian Lourido’s CRISPR screen technique reveals factors in parasites’ susceptibility to antibiotics.