Protein form and function

A new study reveals that the protein MTCH2, which is essential in a variety of cellular processes, is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and provides insight into a variety of MTCH2-linked conditions.

Researchers at Whitehead Institute uncover the 3-D structure of GATOR2, a protein complex that plays a critical role in a signaling pathway that regulates cell growth.

Research from Whitehead Institute Member Peter Reddien’s lab identifies a gene expressed in the skin that covers a wound as essential for regeneration to occur after large injuries in planarians.

A new screening method in the parasite Toxoplasma gondii allows researchers to look beyond whether or not a gene is essential to survival and track the gene’s product through time and physical space 

Researchers in the lab of Whitehead Institute Member Mary Gehring created a new way to study a family of enzymes that control gene expression in plants. Their method reveals how these enzymes affect key decisions in plant development, including when to produce flowers.

Researchers in the lab of Whitehead Institute Member Iain Cheeseman explore the developmental origins of a body plan in bat stars.

A new screening method from the labs of Whitehead Institute Member Jonathan Weissman, Britt Adamson at Princeton University, and Editas Medicine provides a deeper look at how cells repair DNA damage. The method could help researchers assess the action of new gene editing methods.