Page Lab

Research from Whitehead Institute Member David Page’s lab shows that the so-called inactive X chromosome, the mostly silent second X chromosome in females, plays a much more active role in gene expression and gene regulation than previously thought, with implications for how we think about sex differences in health and disease.

Whitehead Institute research projects continue to provide important insights into human biology, and they are paving the way for future treatments to address developmental disorders and diseases.

Rebecca Harris, a physician-scientist at Whitehead Institute’s Brit J. d’Arbeloff Center for Women’s Health, has received a prestigious funding award from the NIH’s Building Interdisciplinary Research Careers in Women's Health (BIRCWH) program.

Genes that remain on these volatile chromosomes are essential for the animal to live, suggests a new paper from the Page Lab at Whitehead Institute

Whitehead Institute attracts people that are driven — and often that means people that bring an impressive level of intensity to their hobbies and side projects, too. Some have leaned on their outside interests to find balance and respite during the COVID-19 pandemic — and often as not, they parlay their interests to contribute to the community at the same time.

Whitehead Institute researchers have sequenced the male-determining chromosome of cattle — and found evidence of a “selfish” competition between sex chromosomes 

Adrianna San Roman is a postdoc in Whitehead Institute Director and Member David Page’s lab investigating sex differences in human health. San Roman’s work is supported by the Arthur W. Brill and Carol Tobin Brill Postdoctoral Fellowship and an NIH Postdoctoral Fellowship. We sat down with San Roman to learn more about her and her experiences in and out of the lab.