News

Filter by:
Filter by:
Lab
Topics

By teasing apart rapamycin’s activity at the cellular level, researchers at Whitehead Institute and the University of Pennsylvania have determined that inhibiting only the protein cluster known as the mechanistic target of rapamycin complex 1 (mTORC1) prolongs life in mice without adversely affecting glucose tolerance or insulin sensitivity.

A team of scientists from Whitehead Institute and other institutions has shown for the first time how two long intergenic noncoding RNAs (ncRNAs) in brewer’s yeast (Saccharomyces cerevisiae) contribute to a location-dependent switch for the yeast FLO11 gene to toggle between active and inactive states.

The entire Whitehead Institute community is profoundly saddened by news of Friday night's passing of John Pratt, the Institute’s former Associate Director and a central figure in establishing what would become one of the world’s preeminent biomedical research institutions.