Whitehead Institute researchers have determined that heat shock protein 90 (Hsp90) can create diverse heritable traits in brewer’s yeast (Saccharomyces cerevisiae) by affecting a large portion of the yeast genome.
By determining how corticosteroids act to increase production of red blood cell progenitors, Whitehead Institute researchers have identified a class of drugs that may be beneficial in treating some erythropoietin-resistant anemias.
Whitehead Institute researchers have linked hyperactivity in the mechanistic target of rapamycin complex 1 (mTORC1) cellular pathway to reduced ketone production in the liver, which is a well-defined physiological trait of aging in mice.
Whitehead Institute Founding Member Rudolf Jaenisch has been named a recipient of the 2011 Warren Triennial Prize of Massachusetts General Hospital (MGH).
Whitehead Institute Member Iain Cheeseman will receive the 2011 R.R. Bensley Award, one of four Young Investigator Awards distributed by the American Association of Anatomists (AAA).
Whitehead Institute researchers have shown in mouse models that overexpression of the microRNA 125b (miR-125b) can independently cause leukemia and accelerate the disease’s progression in mice.