Whitehead Institute researchers advance the predictive model for the influence of microRNAs on gene expression in a cell. Their findings illustrate that high-, medium-, and low-affinity microRNA target sites unexpectedly vary between different microRNAs, and that in some cases they include imperfectly matched sequences.

Vijay Sankaran is an associate professor of pediatrics at Harvard Medical School, interim chief and an attending physician in hematology and oncology at Boston Children’s Hospital and the Dana-Farber Cancer Institute, and an associate member of Broad Institute. We talked to Sankaran about his career, interests, and experiences at Whitehead Institute.