Immune System

Researchers in the lab of Whitehead Institute Founding Member Robert Weinberg have determined how mesenchymal cancer cells may resist treatment, work that may allow them to make once-resistant tumors respond to certain cancer therapies.

Using red blood cells modified to carry disease-specific antigens, a team of scientists from Whitehead Institute and Boston Children’s Hospital have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.  This research is an exciting step toward therapeutics for autoimmune diseases, which affect an estimated 23 million Americans.