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"Regeneration is one of the great mysteries of biology that has puzzled developmental biologists for well over a century," says Whitehead Associate Member Peter Reddien. But that's changing quickly as researchers bring the powerhouses of modern biological analyses to studying these processes-with the hope that a better understanding of regeneration may eventually find medical applications.

Feverishly hot climates. Dizzying alcohol and sugar binges. Heavy metals. Toxic drugs. Genetic mutations. Over the years, yeast, fruit flies, mustard plants and mice have struggled through their own versions of an extreme reality TV show in the laboratory of Whitehead Member Susan Lindquist.