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Whitehead Institute researchers used a new approach for analyzing genetic risk data and discovered that disease-linked genes cause problems in brain cells that contribute to multiple sclerosis, which had been thought of as a solely autoimmune disease. This information could lead to the development of new therapies for multiple sclerosis, and the approach can be applied to gain insights into other diseases.

Maya Mitalipova, director of the Human Stem Cell Facility, isolated some of the first human embryonic stem cell lines confirmed by the National Institutes of Health in 2001. With 18 years of experience with human embryonic stem cells (HSCs) and having isolated 19 HSC lines at Whitehead Institute, Mitalipova says that her knowledge lets her troubleshoot nearly any hurdle that researchers encounter.