Regeneration, rejuvenation, and aging

In this episode of AudioHelicase, we sit down with four Whitehead Institute researchers who are gaining unique insights into biological processes—from regeneration, organ function, and immune response to embryonic development—by studying them within the rich context of their natural environment.

Whitehead Institute Member Siniša Hrvatin and colleagues  show that inducing a prolonged state of dormancy in mice slows down progressive molecular changes associated with aging. The work also identifies decreased body temperature as a central regulator of this anti-aging effect.

In this special episode of AudioHelicase, we talk to three researchers about the cells in our bodies that can regenerate – and those that can’t. We ask, why can some cells no longer renew themselves? And, importantly, can we change that?