News

New paper in Science reveals how mTORC1 docks at lysosomal surface  

Izabella Pena is a postdoc in Whitehead Institute Member David Sabatini’s lab investigating how toxic proteins associated with neurodegeneration are degraded in cells. We sat down with Pena to learn more about her and her experiences in and out of the lab.

Whitehead Institute researchers have discovered that particular signaling pathways, which transmit environmental cues and effect changes in gene expression, rely on phase-separated condensates to find, occupy, and activate the right genes in each cell type

Lehmann, a world renowned developmental and cell biology researcher, will be Whitehead Institute’s fifth Director. 

Vijay Sankaran is an associate professor of pediatrics at Harvard Medical School, interim chief and an attending physician in hematology and oncology at Boston Children’s Hospital and the Dana-Farber Cancer Institute, and an associate member of Broad Institute. We talked to Sankaran about his career, interests, and experiences at Whitehead Institute.

In this video, learn about the ambitious research programs of the two newest members of Whitehead Institute, Pulin Li and Ankur Jain. Li experimentally re-wires genetic circuits that control tissue patterning, with the goal of one day informing regenerative medicine techniques. Jain investigates the biophysics of RNA molecule aggregations, which could lead to cellular dysfunction seen in repeat expansion disorders such as Huntington’s and amyotrophic lateral sclerosis (ALS).

Whitehead Institute researchers unravel the unique biology of apicomplexans — the parasites responsible for malaria, toxoplasmosis, and other diseases impacting global health.