This special podcast episode highlights work from Whitehead Institute researchers about the key players in the cell that keeps all the other parts in harmony.
Whitehead Institute Member Pulin Li talks about how her lab engineers cells in Petri dishes to communicate with each other and form patterns, recreating processes seen in embryodevelopment—and how this work could eventually inform efforts to grow tissues in the lab.
In this episode of AudioHelicase, Whitehead Institute Member Ankur Jain discusses how RNA can clump in cells and the diseases, such as Huntington's and amyotrophic lateral sclerosis (ALS), that are associated with these aggregations.
In this episode of AudioHelicase, Whitehead Institute Member Iain Cheeseman discusses how his work on the kinetochore provides a window into cell division and what happens when this vital cellular function goes awry.
In this episode of AudioHelicase, Whitehead Institute Member Mary Gehring discusses how her research on the plant Arabidopsis thaliana reveals how gene regulation can be passed from one generation to the next.
Whitehead's David Sabatini discusses mTOR, a protein connecting metabolism, nutrition, and disease and the current research in his lab investigating the mTOR pathway and its role in cancer, diabetes, and aging.
From his discovery of the first oncogene and tumor suppressor, to his work revealing critical aspects of the mutational basis of cancer, and more recently its metastatic behavior, Whitehead Founding Member Robert Weinberg’s work has been foundational in our understanding of cancer biology.
Whitehead Member Sebastian Lourido discusses his work uncovering how the Toxoplasma parasite causes disease and the importance of understanding parasitic infections such as toxoplasmosis and malaria in the context of global health.