Cancer

By seeding mouse nervous systems with human cells, researchers have created a system to model human neuroblastoma tumors. 

Benjamin Sabari was a postdoc in Whitehead Institute Member Richard (Rick) Young’s lab investigating how the molecules involved in gene regulation organize into large collective assemblies called condensates. As of January 2020, Sabari is running his own lab at the University of Texas Southwestern Medical Center. We sat down with Sabari to learn more about him and his experiences in and out of the lab.

Whitehead Institute researchers have rewritten the timeline for when and how embryonic cells commit to becoming sex cells, the cells that produce eggs and sperm, and gained insights into the development of testicular cancer.

Anushka Dongre is a postdoc in Whitehead Institute Member Robert (Bob) Weinberg’s lab investigating how cancers spread and how the body’s own immune system can be used to fight them. 

Whitehead Institute and Broad Institute researchers determine that cancer cells commonly change their energy source, creating a weakness that the drug elesclomol exploits to resensitize cancer cells to proteasome inhibitors