News + Publications

Image of a breast cancer cell

October 20, 2017

Stuck on the membrane: A pro-metastatic transcription factor’s journey from anonymity to a promising target for breast cancer therapy

Whitehead Member Piyush Gupta has identified a protein stuck in the cell membrane that plays an important role in a cellular pathway crucial for cancer metastasis. The protein is a potential new target for breast cancer therapy that targets the cancer cells' metastatic behavior. 

Illustration of scientist measuring a cell on a scale

October 19, 2017

Study reveals key molecular link in major cell growth pathway

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.  The researchers’ findings also implicate a new protein, SLC38A9, as a potential drug target in pancreatic cancer. 

Image of zebrafish

October 6, 2017

Genetic body/brain connection identified in genomic region linked to autism

For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes—fam57ba and doc2a—in zebrafish and certain brain and body traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes reside in the 16p11.2 region of the genome, which has been linked to multiple brain and body disorders in humans, including autism spectrum disorder, developmental delays, seizures, and obesity.

Richard Young, Maria Zuber, Kathleen "Kate" Rubins, David Page

September 15, 2017

Whitehead Connects: An Evening With NASA Astronaut Kathleen Rubins

Whitehead Connects was pleased to welcome NASA astronaut and former Whitehead Fellow Kathleen “Kate” Rubins on September 12, 2017.

AudioHelicase logo and Whitehead Member David Sabatini

September 12, 2017

AudioHelicase: The podcast of Whitehead Institute

Whitehead's David Sabatini discusses mTOR, a protein connecting metabolism, nutrition, and disease and the current research in his lab investigating the mTOR pathway and its role in cancer, diabetes, and aging.

Paradigm Magazine


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