News + Publications

Three images of human lung cells were infected with influenza A virus.

June 20, 2016

Tiny alpaca-derived antibodies point to targets preventing viral infection

Using tiny, alpaca-derived, single-domain antibody fragments, Whitehead Institute scientists have developed a method to perturb cellular processes in mammalian cells, allowing them to tease apart the roles that individual proteins play in these pathways. With improved knowledge of protein activity, scientists can better understand not only basic biology but also how disease corrupts cellular function and identify potential therapeutics to rectify these aberrations.

Whitehead Institute Members Hidde Ploegh and David Sabatini

May 3, 2016

Whitehead Members Hidde Ploegh and David Sabatini Elected to National Academy of Sciences

The National Academy of Sciences announced today that Whitehead Institute’s Hidde Ploegh and David Sabatini are among 84 new Academy members elected in recognition of distinguished and continuing achievements in original research.

Photo of plate showing different strengths of prion activity in yeast

April 29, 2016

Prion-like protein found in plants

Whitehead Institute scientists have determined that a plant protein involved in the timing of flowering could in fact be a prion. This is the first time that a possible prion has been identified in plants, and it may play a role in a plant’s “memory” of cold exposure during winter.

Cartoon of how a mutation in the genome's three-dimensional structure can activate previously silent oncogenes

April 20, 2016

Identifying a genetic mutation behind sporadic Parkinson’s disease

Using a novel method, Whitehead Institute researchers have determined how mutations that are not located within genes are identified through genome-wide association studies (GWAS) and can contribute to sporadic Parkinson’s disease, the most common form of the condition. The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer.

Whitehead Founding Member Robert Weinberg

April 14, 2016

Salk Institute honors Whitehead’s Weinberg for research excellence

Whitehead Founding Member Robert Weinberg is one of two scientists to receive the prestigious Salk Institute Medal for Research Excellence, an honor that Salk has bestowed only twice before in its 55-year history.

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