News + Publications

Image of human red blood cells

May 11, 2015

Repurposed anti-cholesterol drug could improve treatment-resistant anemias

Using a mouse model, the lab of Whitehead Institute Founding Member Harvey Lodish, has now determined that combining the cholesterol-lowering drug fenofibrate with glucocorticoids could allow for dramatically lower steroid doses in the treatment of  Diamond Blackfan anemia and other erythropoietin-resistant anemias.

Image of cells with and without RUNX1 turned on

May 6, 2015

Scientists identify gene required for differentiation of breast stem cells

Scientists have applied a new method of analyzing cell states to identify a gene required for breast stem cells to differentiate. This gene, RUNX1, is deregulated or mutated in some leukemias and breast cancers. The novel approach, known as PEACS, could also be used to screen for drugs that activate or inhibit the expression regulators of stem cell differentiation.

May 1, 2015

Whitehead’s Susan Lindquist elected to UK’s Royal Society

The UK’s Royal Society today announced that it has elected Whitehead Institute’s Susan Lindquist as a Foreign Member.

Whitehead Founding Member Rudolf Jaenisch

April 27, 2015

Whitehead’s Rudolf Jaenisch honored with March of Dimes Prize

The prize honors Jaenisch’s groundbreaking body of work in epigenetics, the development of transgenic animals, and the generation and use of induced pluripotent stem (iPS) cells.

Image showing tumors

April 20, 2015

Imaging immunity: Noninvasive imaging of immune system detects tumors, could monitor therapeutic response

A novel approach that allows real-time imaging of the immune system’s response to the presence of tumors—without the need for blood draws or invasive biopsies—offers a potential breakthrough both in diagnostics and in the ability to monitor efficacy of cancer therapies.

Paradigm Magazine


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