Autoimmune disease

Science in 60 breaks down the latest research at Whitehead Institute through one-minute explainers. In this video, Xochitl Luna discusses investigating the role of microglia—the brain’s resident immune cells—in multiple sclerosis.

Using red blood cells modified to carry disease-specific antigens, a team of scientists from Whitehead Institute and Boston Children’s Hospital have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.  This research is an exciting step toward therapeutics for autoimmune diseases, which affect an estimated 23 million Americans.