Autoimmune disease

Science in 60 breaks down the latest research at Whitehead Institute through one-minute explainers. In this video, Xochitl Luna discusses investigating the role of microglia—the brain’s resident immune cells—in multiple sclerosis.

A new experimental system shows how insulin-producing beta cells react under autoimmune attack during type 1 diabetes; the results could lead to better treatments.

Differently shaped RNA molecules allow HIV to express different genes from the same RNA sequence.

Using red blood cells modified to carry disease-specific antigens, a team of scientists from Whitehead Institute and Boston Children’s Hospital have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.  This research is an exciting step toward therapeutics for autoimmune diseases, which affect an estimated 23 million Americans.