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Scientists have known for the last decade that a link exists between wound healing and cancer. Now scientists in the lab of Whitehead Institute Member Robert Weinberg have discovered the process by which tumors hijack normal wound-healing processes and use them for their own purposes.

Cells are dividing all the time, and that’s a good thing. If they didn’t, our tissue and organs couldn’t replenish themselves, and pretty soon we’d be done for. But when cell division goes wrong, it can have disastrous results, such as cancer and birth defects. Scientists in the lab of Whitehead Member Terry Orr-Weaver have uncovered one of the primary mechanisms governing cell division.

2005 is off to a good start for Whitehead Member David Bartel. In January, he and his colleagues published a landmark paper in the journal Cell. A week later he was honored with the National Academy of Science's prestigious Award in Molecular Biology. And in March, Bartel was appointed Investigator for the Howard Hughes Medical Institute (HHMI).

Whitehead Institute has joined ten other leading biomedical organizations in an $18 million, three-year public-private consortium that will create a comprehensive library of gene inhibitors to be made available to the entire scientific community.

For nearly a decade, scientists have been trying to fully understand a particular communication pathway inside of cells that contributes to many malignant brain and prostate cancers.

Researchers from Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology have discovered that a kind of RNA molecule called microRNA regulates more than 5,300 human genes, or nearly one-third of the genome’s protein coding regions.