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The same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain themselves.

Researchers in the lab of Whitehead Institute Member David Bartel have found that a class of small RNAs called microRNAs influence the evolution of genes far more widely than previous research had indicated.

"Regeneration is one of the great mysteries of biology that has puzzled developmental biologists for well over a century," says Whitehead Associate Member Peter Reddien. But that's changing quickly as researchers bring the powerhouses of modern biological analyses to studying these processes-with the hope that a better understanding of regeneration may eventually find medical applications.