When we take in energy as food or drink, a complex suite of chemical reactions allow us to turn it into usable fuel. The sum of these reactions, within each cell and throughout the body, makes up our metabolism. In this multimedia collection, learn how Whitehead Institute researchers are delving into the mechanisms behind metabolism from a variety of angles. Click here to explore the series!
Institute researchers continue to pioneer a deeper understanding of how metabolic processes contribute to health and disease – with long-term implications that could range from new treatments for obesity and type 2 diabetes to methods for slowing the aging process. Here are a few examples of Whitehead Institute scientists’ creative and pioneering work in the field of metabolism.
A group of researchers from multiple universities, including Whitehead Institute Member Olivia Corradin, gained new insights into the genetics of opioid overdose risk by looking at changes in gene regulation in the brain.
Introducing Sinisa Hrvatin, who joined Whitehead Institute as a Member this year. Hrvatin, who completed his postdoc at Harvard Medical School, studies how cells initiate, regulate, and survive states of stasis, including hibernation.
The new WhiteheadInitiative on Biology, Health, and Climate Change (WIBHC) is designed both to explore climate change’s biological impacts and spark biotechnology interventions to counter its detrimental effects. Philanthropic funders have already stepped up to help underwrite two novel WIBHC research projects.
Whitehead Institute Member Jing-Ke Weng studies plant metabolism, the set of processes plants use to produce thousands of unique molecules, many of which have potent medicinal properties. The Weng lab is hunting for more of these molecules in the wild, and developing strategies to sustainably produce plant molecules already of interest at scale.