Tag: Protein Function

Researchers discover receptor molecule for key diabetes protein

June 30, 2004

Obesity researchers made an intriguing discovery in 2001 when they found that large doses of a particular fat-cell protein, adiponectin, caused obese mice to lose weight.

Amyloid fibers exposed to Hsp104

Researchers discover protein that dissolves amyloid fibers

May 20, 2004

Amyloid fibers, those clumps of plaque-like proteins that clog up the brains of Alzheimer’s patients, have perplexed scientists with their robust structures. In laboratory experiments, they are able to withstand extreme heat and cold and powerful detergents that cripple most other proteins.

Yeast’s variety show

February 11, 2004

New research into a family of cell wall proteins shows how yeast can present a variety of “faces” to its environment. In pathogens like yeast, these cell surface proteins regulate how the cell sticks to other cells, interacts with surrounding tissue and evades detection by the immune system.

Studies Examine Development in Drosophila

February 11, 2004

Two studies by scientists in the lab of Whitehead Member Terry Orr-Weaver that shed light on developmental strategies of Drosophila were published in recent issues of the journals Developmental Cell and Current Biology.

“Mad Cow” Mechanism May Be Integral to Storing Memory

December 24, 2003

Scientists have discovered a new process for how memories might be stored, a finding that could help explain one of the least-understood activities of the brain.

The Protein Universe

December 16, 2003

The story of life and all its associated processes takes place within a vast universe of proteins and their interactions, a bountiful frontier ripe for exploration.

Yeast Helps Researchers Better Understand Parkinson's Mystery

December 4, 2003

Scientists know that in patients with Parkinson’s disease, certain proteins in the brain form clusters that somehow contribute to cell death and, eventually, lead to the onset of the disease’s debilitating symptoms. Whitehead scientists have succeeded in duplicating the disease’s most critical features in the most readily manipulated model organism in existence.

Scientists Identify Dual Function for “Eyes absent”

November 19, 2003

Scientists know that proteins called transcription factors that regulate gene expression play a key role in cellular function. But what if that’s only part of the story? What if these regulators lead a double life no one knew before?

Scientists Work to Break Cellular Code

November 6, 2003

Despite the rich knowledge scientists now have of the genes that constitute the human genome, researchers have yet to unravel the precise choreography by which they work – or malfunction – together in the cell in response to triggers from the outside world.

Study Offers New Insight into Rett Syndrome

October 30, 2003

Rett Syndrome is a major cause of mental retardation in girls. Although researchers have identified the protein involved in the disease, its exact role remains a mystery. Now, a group of researchers from Children’s Hospital Boston and Whitehead Institute have identified the protein’s function, a discovery the scientists say could be the first significant advance in Rett Syndrome research in years.

New Protein Provides Clue to Diabetes

October 15, 2003

Although cases of adult-onset diabetes have skyrocketed in the United States, researchers still don’t know much about the biological processes that predispose so many people to the disease. But in research that will be published in the Oct. 16 issue of the journal Nature, scientists say they’ve found a protein that plays an essential role in regulating a cell’s ability to absorb glucose.

New Computer Method Advances Systems Biology

October 14, 2003

A team of researchers from Whitehead Institute and MIT have developed a new computational method that will give a boost to the field of systems biology.

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