Whitehead Institute Member Ankur Jain Receives Packard Foundation Fellowship
October 15, 2019
The Packard Foundation Fellowships are one of the most prestigious and well-funded non-governmental awards for early career scientists
Tag: Neurobiology
Epigenetics: Chemical guideposts for gene expression
September 30, 2019
Whitehead Institute researchers investigate methylation, the chemical tags that help define gene expression during development and disease
Looking Beyond the Gene: An Introduction
September 30, 2019
Whitehead Institute researchers are uncovering new ways that genes are regulated that upend existing paradigms of gene expression and provide important insights into health and disease. This collection of stories and multimedia explores that research.
Video - BUILDING FROM THE BOTTOM UP: NEW MEMBERS OF WHITEHEAD INSTITUTE EXPLORE THE FUNDAMENTALS OF BIOLOGY
September 4, 2019
Whitehead Institute Members Pulin Li and Ankur Jain are pursuing exciting new research directions, expanding the scope of science at the Institute
Video - BUILDING FROM THE BOTTOM UP: NEW MEMBERS OF WHITEHEAD INSTITUTE EXPLORE THE FUNDAMENTALS OF BIOLOGY
September 4, 2019
Whitehead Institute Members Pulin Li and Ankur Jain are pursuing exciting new research directions, expanding the scope of science at the Institute
Speeding up drug discovery for brain diseases
July 31, 2019
Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder
How to be a good host (for Zika virus)
April 22, 2019
Using a genome-wide CRISPR screen in neural progenitor cells, Whitehead Institute scientists uncover what the Zika virus needs to infect human cells
Only in your head
October 9, 2018
Researchers uncover how a ubiquitously expressed mutation causes a brain-specific disorder.
Stem cell-derived Zika model suggests mechanisms underlying microcephaly
June 19, 2018
Infected microglia cells can ferry Zika virus to developing brain
Network of diverse noncoding RNAs acts in the brain
June 7, 2018
First known network consisting of three types of regulatory RNAs is identified
Genetic body/brain connection identified in genomic region linked to autism
October 6, 2017
For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes—fam57ba and doc2a—in zebrafish and certain brain and body traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes reside in the 16p11.2 region of the genome, which has been linked to multiple brain and body disorders in humans, including autism spectrum disorder, developmental delays, seizures, and obesity.
Derived neural immune cells enable new facet of neurodegeneration research
September 26, 2016
Whitehead Institute scientists have devised a protocol for pushing human pluripotent stem cells to become microglia—the specialized immune cells that maintain the brain and care for it after injury. Microglia play an important role in neurodegenerative diseases, including Parkinson’s and Alzheimer’s, and studying these cells has been very difficult until now.