Tag: Genetics + Genomics

Illustration of scientist letting genie DNA out of a pot

Looking Beyond the Gene: An Introduction

September 30, 2019

Whitehead Institute researchers are uncovering new ways that genes are regulated that upend existing paradigms of gene expression and provide important insights into health and disease. This collection of stories and multimedia explores that research.

Image of methylation in mouse embryos

Epigenetics: Chemical guideposts for gene expression

September 30, 2019

Whitehead Institute researchers investigate methylation, the chemical tags that help define gene expression during development and disease

Illustration of a hairpin loop from a pre-mRNA

Regulatory RNA: The sculptors of gene expression

September 30, 2019

Whitehead Institute scientists have been uncovering the roles of regulatory RNA in controlling gene expression

Illustration of moths around a light

Signaling factor seeking gene

September 25, 2019

Whitehead Institute researchers have discovered that particular signaling pathways, which transmit environmental cues and effect changes in gene expression, rely on phase-separated condensates to find, occupy, and activate the right genes in each cell type

Video - BUILDING FROM THE BOTTOM UP: NEW MEMBERS OF WHITEHEAD INSTITUTE EXPLORE THE FUNDAMENTALS OF BIOLOGY

September 4, 2019

Whitehead Institute Members Pulin Li and Ankur Jain are pursuing exciting new research directions, expanding the scope of science at the Institute

Video - BUILDING FROM THE BOTTOM UP: NEW MEMBERS OF WHITEHEAD INSTITUTE EXPLORE THE FUNDAMENTALS OF BIOLOGY

September 4, 2019

Whitehead Institute Members Pulin Li and Ankur Jain are pursuing exciting new research directions, expanding the scope of science at the Institute

Illustration of a train on a DNA track between droplets

An emerging view of RNA transcription and splicing

August 7, 2019

Whitehead Institute scientists discover that chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression

Illustration of person using a claw machine to pick out a drug candidate

Speeding up drug discovery for brain diseases

July 31, 2019

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder

Photo showing the bell curve of women's and men's heights

Genetic study takes sex differences research to new heights

July 18, 2019

Researchers find differences in gene expression between males and females throughout the body in humans and other mammals, including ones that contribute to the average height difference between the sexes

Representation of the Zika virus's surface

How to be a good host (for Zika virus)

April 22, 2019

Using a genome-wide CRISPR screen in neural progenitor cells, Whitehead Institute scientists uncover what the Zika virus needs to infect human cells

Illustration of egg with sperm swimming toward it

A troubling inheritance

April 9, 2019

Researchers have found that certain epigenetic changes in mice that appear to be inherited by offspring can lead to increased cancer rates

Photo of Postdoc Shawn Liu and Whitehead Institute Member Rudolf Jaensich with STAT logo

Whitehead Institute researchers win STAT's Editor's Pick award

April 8, 2019

Whitehead Institute Member Rudolf Jaenisch and Shawn Liu, a postdoc in his lab, were chosen for the honor by STAT staff

Pages

© Whitehead Institute for Biomedical Research              455 Main Street          Cambridge, MA 02142