Tag: Genetics + Genomics

A split image shows healthy and diseased airway cilia side by side. The healthy cilia are well-defined, the diseased look a little shapeless and stuck together.

From bedside to bench, and back again

April 22, 2020

A mysterious case in the clinic led Whitehead Institute researchers to discover a new genetic lung condition

To be long-lived or short-lived?

February 20, 2020

Whitehead team offers sweeping view of messenger RNA stability and degradation across thousands of genes

Photo of Whitehead Institute member Gerald Fink

Gerald Fink is Awarded the Genetic Society of America’s Thomas Hunt Morgan Medal

January 29, 2020

In honoring him with the Thomas Hunt Morgan Medal, GSA is recognizing Fink’s discovery of principles central to genome organization and regulation in eukaryotic cells.

A Toxoplasma cyst isolated from a mouse brain. The cyst wall is stained green and the parasites are stained magenta.

Putting a finger on the switch of chronic parasite infection

January 16, 2020

Researchers at Whitehead Institute have discovered the master regulator necessary for the pervasive parasite Toxoplasma gondii to chronically infect its host. This finding provides important insights into the parasite’s biology and allows scientists in the laboratory to control if and when the parasite can differentiate into its chronic stage, which may inform research into prevention and treatment of infection.

Group photo of Brit d’Arbeloff and David Page (both seated) with Page lab postdoctoral fellow Adrianna San Roman (left) and Sahin Naqvi (rear), then a Page lab graduate student and now a postdoctoral fellow at Stanford University.

Whitehead Institute Receives $10 Million Gift to Study Sex Chromosomes’ Impact on Women's Health and Disease

January 9, 2020

The gift establishes the Brit Jepson d’Arbeloff Center on Women's Health within the Institute’s Sex Differences in Health and Disease Initiative

Embryonic testis with PGCs in red

Committed to reproduction

November 21, 2019

Whitehead Institute researchers have rewritten the timeline for when and how embryonic cells commit to becoming sex cells, the cells that produce eggs and sperm, and gained insights into the development of testicular cancer.

Illustration of a hairpin loop from a pre-mRNA

Regulatory RNA: The sculptors of gene expression

September 30, 2019

Whitehead Institute scientists have been uncovering the roles of regulatory RNA in controlling gene expression

Illustration of scientist letting genie DNA out of a pot

Looking Beyond the Gene: An Introduction

September 30, 2019

Whitehead Institute researchers are uncovering new ways that genes are regulated that upend existing paradigms of gene expression and provide important insights into health and disease. This collection of stories and multimedia explores that research.

Image of methylation in mouse embryos

Epigenetics: Chemical guideposts for gene expression

September 30, 2019

Whitehead Institute researchers investigate methylation, the chemical tags that help define gene expression during development and disease

Illustration of moths around a light

Signaling factor seeking gene

September 25, 2019

Whitehead Institute researchers have discovered that particular signaling pathways, which transmit environmental cues and effect changes in gene expression, rely on phase-separated condensates to find, occupy, and activate the right genes in each cell type

Video - BUILDING FROM THE BOTTOM UP: NEW MEMBERS OF WHITEHEAD INSTITUTE EXPLORE THE FUNDAMENTALS OF BIOLOGY

September 4, 2019

Whitehead Institute Members Pulin Li and Ankur Jain are pursuing exciting new research directions, expanding the scope of science at the Institute

Video - BUILDING FROM THE BOTTOM UP: NEW MEMBERS OF WHITEHEAD INSTITUTE EXPLORE THE FUNDAMENTALS OF BIOLOGY

September 4, 2019

Whitehead Institute Members Pulin Li and Ankur Jain are pursuing exciting new research directions, expanding the scope of science at the Institute

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