Whitehead Institute for Biomedical Research

Knowing where you came from

Whitehead Member Mary Gehring  studies how gene expression is regulated by the addition and removal of DNA methylation from the genome. In this image of an Arabidopsis thaliana flower, the veins of the sepals, filaments of the anthers, and base of the stigma are highlighted by a marked enzyme that is essential to this type of gene regulation. 

Image by Deborah Pohlmann/Whitehead Institute

About

Step inside Whitehead Institute to see and hear what makes this unique biomedical research community so special.


Podcast

AudioHelicase logo with Sebastian Lourido

November 20, 2017

AudioHelicase: Whitehead’s Sebastian Lourido on Toxoplasma, malaria parasites, and global health.

Whitehead Member Sebastian Lourido studies a group of parasites called the Apicomplexa. These single-celled organisms are among the most common pathogens and are capable of causing devastating diseases in humans and animals, including toxoplasmosis, malaria, and infant diarrhea.


events

Image of Jim Simons

Whitehead Connects presents Jim Simons on November 30

Dr. James H. Simons's presentation, "Mathematics, Common Sense, and Good Luck", will be followed by a networking session. Simons is the chairman of the Simons Foundation, an organization dedicated to advancing the frontiers of research in mathematics and the basic sciences.

In the News

Image of plants with curled leaves due to lack of gene methylation

December 14, 2017

Epigenetic rheostat helps uncover how gene regulation is inherited and maintained

DNA Methylation—the addition of chemical tags to DNA—typically reduces the expression of methylated genes. Whitehead Institute Member Mary Gehring and her lab have identified a mechanism important for maintaining methylation, that when disrupted, results in the demethylation of large sections of the Arabidopsis plant’s genome.

 


 

Illustration of neighborhoods within DNA loops

NEW STUDY PROMPTS RETHINKING TRANSCRIPTION FACTOR’S ROLE IN CONTROL OF GENE EXPRESSION

DECEMBER 7, 2017

Like proteins, genomes must fold appropriately to function properly; some transcription factors provide the structural support.

Featured

TENURE TRACK FACULTY POSITIONS AT WHITEHEAD Institute/MIT

Whitehead Institute and the Department of Biology at MIT are seeking outstanding scientists for two tenure track faculty positions at the Assistant Professor level.

Whitehead Institute and MIT Biology logos


Image of planarians

SURPRISING ROLES FOR MUSCLE IN TISSUE REGENERATION, STUDY FINDS

NOVEMBER 22, 2017

Whitehead Member Peter Reddien pinpoints distinct muscle subsets that orchestrate and pattern regrowth



Cover of Fall 2017 issue of Paradigm

Fall 2017 Issue of Paradigm

Paradigm magazine reports on Whitehead Institute research, trends in the life sciences, and happenings in the Whitehead community

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Whitehead Institute relies heavily on philanthropy to maintain its pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics, and genomics. Gifts from individual donors, foundations, and corporations directly support Whitehead scientists pursuing breakthroughs that are transforming our understanding of biology and accelerating the development of therapies for a host of intractable human diseases.

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