Whitehead Institute for Biomedical Research

Knowing where you came from

Whitehead Member Mary Gehring  studies how gene expression is regulated by the addition and removal of DNA methylation from the genome. In this image of an Arabidopsis thaliana flower, the veins of the sepals, filaments of the anthers, and base of the stigma are highlighted by a marked enzyme that is essential to this type of gene regulation. 

Image by Deborah Pohlmann/Whitehead Institute

About

Step inside Whitehead Institute to see and hear what makes this unique biomedical research community so special.


Podcast

AudioHelicase logo and Whitehead Member David Sabatini

SEPTEMBER 12, 2017

AUDIOHELICASE: THE PODCAST OF WHITEHEAD INSTITUTE

Whitehead's David Sabatini discusses mTOR, a protein connecting metabolism, nutrition, and disease and the current research in his lab investigating the mTOR pathway and its role in cancer, diabetes, and aging.

In the News

Illustration of scientist measuring a cell on a scale

October 19, 2017

Study reveals key molecular link in major cell growth pathway

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.  The researchers’ findings also implicate a new protein, SLC38A9, as a potential drug target in pancreatic cancer. 

 


 

Image of breast cancer cell

October 20, 2017

Stuck on the membrane: A pro-metastatic transcription factor’s journey from anonymity to a promising target for breast cancer therapy

Whitehead Member Piyush Gupta has identified a protein stuck in the cell membrane that plays an important role in a cellular pathway crucial for cancer metastasis. The protein is a potential new target for breast cancer therapy that targets the cancer cells' metastatic behavior.

Featured

TENURE TRACK FACULTY POSITIONS AT WHITEHEAD Institute/MIT

Whitehead Institute and the Department of Biology at MIT are seeking outstanding scientists for two tenure track faculty positions at the Assistant Professor level.

Whitehead Institute and MIT Biology logos


Image of zebrafish

OCTOBER 6, 2017

GENETIC BODY/BRAIN CONNECTION IDENTIFIED IN GENOMIC REGION LINKED TO AUTISM

For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes—fam57ba and doc2a—in zebrafish and certain brain and body traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes reside in the 16p11.2 region of the genome, which has been linked to multiple brain and body disorders in humans, including autism spectrum disorder, developmental delays, seizures, and obesity.

Support

Please consider making a gift to Whitehead today

Whitehead Institute relies heavily on philanthropy to maintain its pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics, and genomics. Gifts from individual donors, foundations, and corporations directly support Whitehead scientists pursuing breakthroughs that are transforming our understanding of biology and accelerating the development of therapies for a host of intractable human diseases.

Support Whitehead Institute

© Whitehead Institute for Biomedical Research              455 Main Street          Cambridge, MA 02142