Whitehead Institute for Biomedical Research

Development of a membrane

A key enzyme in a neurodevelopmental disorder studied by Whitehead Institute Member Hazel Sive's lab is found to maintain normal membrane organization in cells of the brain. In this image of a mutant embryonic zebrafish brain, we see aggregates of regions in the membrane that are important for signaling and proper protein localization.

Image by Danielle Tomasello/Whitehead Institute

Podcast

AudioHelicase logo with Ankur Jain

February 19, 2019

AudioHelicase podcast: Ankur Jain on RNA clumps and the neurodegenerative diseases associated with them

Jain discusses how RNA can clump in cells and the diseases, such as Huntington's and amyotrophic lateral sclerosis (ALS), that are associated with these aggregations.


video

Still image from video: Like Pearls on a String

MARCH 27, 2019

VIDEO: LIKE PEARLS ON A STRING — A NEW MODEL FOR GENE REGULATION

Learn how Institute Member Richard Young’s lab is transforming our model of gene regulation by uncovering the role of droplets of transcription machinery in activating genes


MultiMedia

Nymphaea thermarum

MARCH 18, 2019

MULTIMEDIA FEATURE: UNUSUAL LABMATES: THE WORLD’S SMALLEST WATER LILY

Experience a multimedia story about Nymphaea thermarum, including how the extinct-in-the-wild plant ended up at Whitehead Institute and what researchers hope to learn from investigating its biology

In the News

Collage of images in regeneration piece: Planarians, liver cells, and stem cells

June 17, 2019

The science of self-repair: regeneration research at Whitehead Institute

Researchers at Whitehead Institute are uncovering the underlying genetics, mechanisms, and principles of regeneration. 


Photo of Whitehead Institute Postdoc Izabella Pena

JUNE 10, 2019

WHITEHEAD INSTITUTE POSTDOC IZABELLA PENA SELECTED AS A 2019 PEW LATIN AMERICAN FELLOW

Pena, who hails from Brazil, studies in Whitehead Institute Member David Sabatini's lab how cells calibrate their growth, metabolism, and proliferation based on nutrient availability 

Announcements

Whitehead Institute Member Pulin Li

APRIL 2, 2019

PULIN LI JOINS WHITEHEAD INSTITUTE

Whitehead Institute announced today that the developmental and synthetic biologist Pulin Li will join the Institute in May as its newest Member.


Photo of Whitehead Institute exterior

MARCH 27, 2019

DAVID C. PAGE TO CONCLUDE TERM AS DIRECTOR

Search committee chaired by former MIT President Susan Hockfield will identify new director for Whitehead Institute


featured

Illustration of a mitochondrion

MAY 27, 2019

DRUG-RESISTANT CANCER CELLS CREATE OWN ACHILLES HEEL

Whitehead Institute and Broad Institute researchers determine that cancer cells commonly change their energy source, creating a weakness that the drug elesclomol exploits to resensitize cancer cells to proteasome inhibitor

Support

Please consider making a gift to Whitehead today

Whitehead Institute relies heavily on philanthropy to maintain its pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics, and genomics. Gifts from individual donors, foundations, and corporations directly support Whitehead scientists pursuing breakthroughs that are transforming our understanding of biology and accelerating the development of therapies for a host of intractable human diseases.

Support Whitehead Institute

© Whitehead Institute for Biomedical Research              455 Main Street          Cambridge, MA 02142