Whitehead Institute for Biomedical Research

Development of a membrane

A key enzyme in a neurodevelopmental disorder studied by Whitehead Institute Member Hazel Sive's lab is found to maintain normal membrane organization in cells of the brain. In this image of a mutant embryonic zebrafish brain, we see aggregates of regions in the membrane that are important for signaling and proper protein localization.

Image by Danielle Tomasello/Whitehead Institute

Podcast

AudioHelicase logo with Ankur Jain

February 19, 2019

AudioHelicase podcast: Ankur Jain on RNA clumps and the neurodegenerative diseases associated with them

Jain discusses how RNA can clump in cells and the diseases, such as Huntington's and amyotrophic lateral sclerosis (ALS), that are associated with these aggregations.


video

Still image from video: Like Pearls on a String

MARCH 27, 2019

VIDEO: LIKE PEARLS ON A STRING — A NEW MODEL FOR GENE REGULATION

Learn how Institute Member Richard Young’s lab is transforming our model of gene regulation by uncovering the role of droplets of transcription machinery in activating genes


MultiMedia

Nymphaea thermarum

MARCH 18, 2019

MULTIMEDIA FEATURE: UNUSUAL LABMATES: THE WORLD’S SMALLEST WATER LILY

Experience a multimedia story about Nymphaea thermarum, including how the extinct-in-the-wild plant ended up at Whitehead Institute and what researchers hope to learn from investigating its biology

In the News

Representation of the Zika virus's surface

April 22, 2019

How to be a good host (for Zika virus)

Using a genome-wide CRISPR screen in neural progenitor cells, Whitehead Institute scientists uncover what the Zika virus needs to infect human cells


Whitehead Institute Member Gerald Fink

APRIL 16, 2019

PUSHING BEYOND THE CENTRAL DOGMA

A standing-room-only audience of faculty and students from Massachusetts Institute of Technology (MIT) offered rapt attention as Whitehead Institute Founding Member and former director Gerald R. Fink delivered MIT’s prestigious Killian Award Lecture


Illustration of egg with sperm swimming toward it

APRIL 9, 2019

A TROUBLING INHERITANCE

Researchers have found that certain epigenetic changes in mice that appear to be inherited by offspring can lead to increased cancer rates

Events

Illustration of scientist and trees

MARCH 7, 2019

SPRING INTO SCIENCE EVENING LECTURE SERIES

Join Whitehead Institute for Spring into Science, an evening lecture series for the Cambridge community featuring the latest in biomedical research. 


Announcements

Whitehead Institute Member Pulin Li

APRIL 2, 2019

PULIN LI JOINS WHITEHEAD INSTITUTE

Whitehead Institute announced today that the developmental and synthetic biologist Pulin Li will join the Institute in May as its newest Member. 


Photo of Whitehead Institute exterior

MARCH 27, 2019

DAVID C. PAGE TO CONCLUDE TERM AS DIRECTOR

Search committee chaired by former MIT President Susan Hockfield will identify new director for Whitehead Institute

Support

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Whitehead Institute relies heavily on philanthropy to maintain its pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics, and genomics. Gifts from individual donors, foundations, and corporations directly support Whitehead scientists pursuing breakthroughs that are transforming our understanding of biology and accelerating the development of therapies for a host of intractable human diseases.

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