Whitehead Institute for Biomedical Research

When More is Better

Most cells in the body have two copies of each chromosome. But some cells,
including the sub-perineurial glia cells (nuclei labeled green) encasing this larval fruit fly brain
lobe, have an increase in DNA copy number. By studying cells like these, Whitehead Member
Terry Orr-Weaver investigates how and why cells increase or decrease copies of their DNA.

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News

February 23, 2017

Researchers uncover a role for HSP90 in gene-environment interactions in humans

Researchers at Whitehead Institute have now uncovered a role for the protein-folding chaperone HSP90 in humans, not only as a modifier of the effects of mutations, but as a mediator of the impact of the environment on the function of mutant proteins. And these effects of HSP90 can alter the course of human diseases.

Featured

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SEMINAR SERIES FOR HIGH SCHOOL TEACHERS

The program, which begins in October, offers educators the opportunity to explore topics at the forefront of biomedical research and incorporate new ideas into their classrooms. 

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