Whitehead Institute for Biomedical Research

When More is Better

Most cells in the body have two copies of each chromosome. But some cells,
including the sub-perineurial glia cells (nuclei labeled green) encasing this larval fruit fly brain
lobe, have an increase in DNA copy number. By studying cells like these, Whitehead Member
Terry Orr-Weaver investigates how and why cells increase or decrease copies of their DNA.

A scientific community exploring biology's most fundamental questions for the betterment of human health

Bartel Lab: Exploring small RNAs that regulate gene expression

Cheeseman Lab: Examining the kinetochore’s role in chromosome segregation and cell division

Fink Lab: Identifying the function of genes involved in intractable fungal infections

Gehring Lab: Studying epigenomic reprogramming during plant reproduction

Gupta Lab: Studying mechanisms that control cellular diversity in normal and cancerous tissues

Jaenisch Lab: Pursuing patient-specific pluripotent cells with which to study complex human diseases

Lindquist Lab: Exploring the ways protein folding determines an organism’s biological properties

Lodish Lab: Elucidating the mechanisms and modulators of red blood cell development

Orr-Weaver Lab: Studying DNA replication, chromosome segregation, and meiosis in the context of organismal development

Page Lab: Shedding new light on sex chromosome biology and evolution, the fetal origins of gametes, and infertility

Ploegh Lab: Elucidating the immune system’s response to invading viruses and bacteria

Reddien Lab: Investigating the cellular and molecular basis for regeneration

Sabatini Lab: Investigating the complex roles nutrients, cell growth, and metabolism play in aging and disease

Sive Lab: Using zebrafish to study vertebrate brain development and the genetic basis of human mental health disorders

Weinberg Lab: Deciphering the drivers of cancer cell invasion and metastasis

Weng Lab: Studying plant metabolism and its link to complex disease biology

Young Lab: Mapping the regulatory circuitry that controls cell state and differentiation in mice and humans

About

JW Player goes here

Step inside Whitehead Institute to see and hear what makes this unique biomedical research community so special.

News

Image showing tumors

April 20, 2015

Imaging immunity: Noninvasive imaging of immune system detects tumors, could monitor therapeutic response

A novel approach that allows real-time imaging of the immune system’s response to the presence of tumors—without the need for blood draws or invasive biopsies—offers a potential breakthrough both in diagnostics and in the ability to monitor efficacy of cancer therapies.

Featured

CampBio student talking to scientist


CampBio - A SUMMER SCIENCE PROGRAM FOR MIDDLE SCHOOL STUDENTS

Inquisitive by nature? Fascinated by living things and how they work? Then join Science from Scientists and Whitehead Institute this summer at CampBio, where curiosity meets real world science, and no question is off-limits. Registration is now open.

Support

Please consider making a gift to Whitehead today

Whitehead Institute relies heavily on philanthropy to maintain its pioneering programs in cancer research, immunology, developmental biology, stem cell research, regenerative medicine, genetics, and genomics. Gifts from individual donors, foundations, and corporations directly support Whitehead scientists pursuing breakthroughs that are transforming our understanding of biology and accelerating the development of therapies for a host of intractable human diseases.

Support Whitehead Institute

© Whitehead Institute for Biomedical Research         Nine Cambridge Center    Cambridge, MA 02142