Tag: Jaenisch Lab

Type 1 diabetes from a beta cell’s perspective

September 24, 2020

A new experimental system shows how insulin-producing beta cells react under autoimmune attack during type 1 diabetes; the results could lead to better treatments

Proteins — and labs — coming together to prevent Rett syndrome

July 22, 2020

New discoveries about the disruption of condensates in the neurodevelopmental disorder Rett syndrome provide insights into how cells compartmentalize chromosomes as well as new potential paths for therapies.

Chimeras offer a new way to study childhood cancers in mice

March 4, 2020

By seeding mouse nervous systems with human cells, researchers have created a system to model human neuroblastoma tumors. 

microglia

Whitehead Institute team develops new method to study human brain cells

November 26, 2019

Approach could accelerate studies of Alzheimer’s and Parkinson’s disease and other brain disorders

Illustration of scientist letting genie DNA out of a pot

Looking Beyond the Gene: An Introduction

September 30, 2019

Whitehead Institute researchers are uncovering new ways that genes are regulated that upend existing paradigms of gene expression and provide important insights into health and disease. This collection of stories and multimedia explores that research.

Image of methylation in mouse embryos

Epigenetics: Chemical guideposts for gene expression

September 30, 2019

Whitehead Institute researchers investigate methylation, the chemical tags that help define gene expression during development and disease

Illustration of person using a claw machine to pick out a drug candidate

Speeding up drug discovery for brain diseases

July 31, 2019

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder

Collage of images in regeneration piece: Planarians, liver cells, and stem cells

The science of self-repair: regeneration research at Whitehead Institute

June 17, 2019

Researchers at Whitehead Institute are uncovering the underlying genetics, mechanisms, and principles of regeneration. 

Representation of the Zika virus's surface

How to be a good host (for Zika virus)

April 22, 2019

Using a genome-wide CRISPR screen in neural progenitor cells, Whitehead Institute scientists uncover what the Zika virus needs to infect human cells

Photo of Postdoc Shawn Liu and Whitehead Institute Member Rudolf Jaensich with STAT logo

Whitehead Institute researchers win STAT's Editor's Pick award

April 8, 2019

Whitehead Institute Member Rudolf Jaenisch and Shawn Liu, a postdoc in his lab, were chosen for the honor by STAT staff

Illustration of a hand assembling a brain jigsaw puzzle

Only in your head

October 9, 2018

Researchers uncover how a ubiquitously expressed mutation causes a brain-specific disorder.

Astrocytes infected with Zika virus

Stem cell-derived Zika model suggests mechanisms underlying microcephaly

June 19, 2018

Infected microglia cells can ferry Zika virus to developing brain

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