Tag: RNA

Putting microRNAs on the stem cell map

August 7, 2008

Short snippets of RNA called microRNAs help to keep embryonic stem cells in their stem cell state. Researchers now have discovered the gene circuitry that controls microRNAs in embryonic stem cells.

How short RNAs influence many proteins

July 30, 2008

The first large-scale study of the protein output of genes targeted by microRNAs confirms that each microRNA adjusts the production of many proteins, and sheds important light on how this regulation occurs.

Single microRNA fine-tunes innate immune response

February 17, 2008

A single microRNA, microRNA-223, in mice controls the production and activation of granulocytes, white blood cells essential for host defense against invading pathogens.

MicroRNA convicted of triggering metastasis

September 26, 2007

Overabundance of a single microRNA can cause tumors to spread to distant tissues in mice.

MicroRNA helps prevent tumors

February 22, 2007

A microRNA directly regulates a gene implicated in human cancers.

Scientists discover new class of RNAs

January 10, 2007

Their uniform structure strongly indicates an important biological role.

Image of yeast cells, some of which have undergone aberrant meiotic events

Scientists discover role for dueling RNAs

November 16, 2006

Researchers have found that a class of RNA molecules, previously thought to have no function, may in fact protect sex cells from self-destructing.

Graphic of RNAi and its role in testing cancer drugs

Silencing cancer

June 7, 2006

Thijn Brummelkamp accelerates genetics research with RNA interference screens.

Image of Arabidopsis thaliana seedlings

When RNA rules

May 5, 2006

A newly discovered class of molecules plays an astonishingly powerful role in biology.

MicroRNAs shape evolution of most genes

November 29, 2005

Researchers in the lab of Whitehead Institute Member David Bartel have found that a class of small RNAs called microRNAs influence the evolution of genes far more widely than previous research had indicated.

RNAi Consortium to accelerate genetic research

March 16, 2005

Whitehead Institute has joined ten other leading biomedical organizations in an $18 million, three-year public-private consortium that will create a comprehensive library of gene inhibitors to be made available to the entire scientific community.

One-third of human genome regulated by RNA

January 14, 2005

Researchers from Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology have discovered that a kind of RNA molecule called microRNA regulates more than 5,300 human genes, or nearly one-third of the genome’s protein coding regions.

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