Tag: Evolution + Development

Uncovering the “must-haves” of tissue regeneration

November 27, 2018

Biological program triggered by large injuries not required for regeneration, Whitehead Institute team finds

Slide of a plant embryo

Plant characteristics shaped by parental conflict

November 19, 2018

Differences in common traits within a plant species, such as seed size, can be determined by more than gene sequence.

Image of goji berries

Heart-healthy plant chemistry

October 29, 2018

A novel genomic approach helps identify medicinal compounds in plants.

Firefly on leaf; Radim Schreiber - FireflyExperience.org

How many evolutionary events can it take to screw in nature’s lightbulb?

October 16, 2018

Firefly genomics reveals independent evolution of bioluminescence in beetles

Illustration of a brain containing RNAs

Network of diverse noncoding RNAs acts in the brain

June 7, 2018

First known network consisting of three types of regulatory RNAs is identified

Three-eyed planarians

A Blueprint for Regeneration

March 15, 2018

Researchers at Whitehead Institute have uncovered a framework for regeneration that may explain and predict how stem cells in adult, regenerating tissue determine where to form replacement structures.

Image of mouse spermatocyte, which is the source of retinoic acid

Retinoic acid regulates transitions in mouse sperm production

November 7, 2017

Researchers swimming upstream in reproductive technology work now have important insights into sperm production

Illustration of scientist looking at tree of life including acoel and planarian

Small worm muscles up to reveal ancient body patterning mechanism during regeneration

October 30, 2017

Whitehead Member Peter Reddien has determined that a major function of muscle in planaria and acoels--a small regenerative marine worm auspiciously located on the evolutionary tree as an outgroup to all the rest of the Bilateria--is to serve as the source of instructive positional information for instructing regeneration.

Jaw-dropping research explains mouth formation during embryonic development

August 2, 2016

Whitehead Institute researchers have identified an area in the developing face of embryonic frogs that unzips to form the mouth. The scientists, who named this region the “pre-mouth array”, have also discovered the cellular signaling that triggers its formation. Elucidating this critical aspect of craniofacial development in a model organism enhances understanding of and potential treatment for human facial birth defects.

New methodology tracks changes in DNA methylation in real time at single-cell resolution

September 24, 2015

Whitehead Institute researchers have developed a tool that allows scientists to monitor changes in DNA methylation over time in individual cells. Certain diseases, including cancer, cause changes in DNA methylation patterns, and the ability to document these alterations could aid in the development of novel therapies.

Detailed depiction of the structure of the mouse Y chromosome

What’s mighty about the mouse? For starters, its massive Y chromosome

October 30, 2014

An exhaustive effort to sequence the mouse Y chromosome reveals a surprisingly large and complex biological beast, at the same time providing remarkable insight into a heated battle for supremacy between mammalian sex chromosomes.

Image of yeast cells

Scientists develop novel approach to boost biofuel production

October 2, 2014

MIT and Whitehead Institute researchers have identified a new way to boost yeast tolerance to ethanol simply by altering the composition of the medium in which the yeast are grown. They believe this finding could have a significant impact on industrial biofuel production.

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