These muscle cells are guideposts to help regenerative flatworms grow back their eyes
June 25, 2020
A new study from Peter Reddien's Lab at Whitehead Institute is a step forward in understanding how neural circuits could be regenerated in adults
Tag: Evolution + Development
Committed to reproduction
November 21, 2019
Whitehead Institute researchers have rewritten the timeline for when and how embryonic cells commit to becoming sex cells, the cells that produce eggs and sperm, and gained insights into the development of testicular cancer.
Epigenetics: Chemical guideposts for gene expression
September 30, 2019
Whitehead Institute researchers investigate methylation, the chemical tags that help define gene expression during development and disease
Regulatory RNA: The sculptors of gene expression
September 30, 2019
Whitehead Institute scientists have been uncovering the roles of regulatory RNA in controlling gene expression
Looking Beyond the Gene: An Introduction
September 30, 2019
Whitehead Institute researchers are uncovering new ways that genes are regulated that upend existing paradigms of gene expression and provide important insights into health and disease. This collection of stories and multimedia explores that research.
Signaling factor seeking gene
September 25, 2019
Whitehead Institute researchers have discovered that particular signaling pathways, which transmit environmental cues and effect changes in gene expression, rely on phase-separated condensates to find, occupy, and activate the right genes in each cell type
To divide or not to divide?
August 15, 2019
Whitehead Institute team reveals molecular program that controls cells’ capacity for division
Speeding up drug discovery for brain diseases
July 31, 2019
Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder
Multi “-omics” approach uncovers the riches of traditional global medicine
July 22, 2019
Researchers solve how the kava plant produces its pain-relieving and anti-anxiety molecules, and demonstrate an extensible method to scale and optimize their production
Genetic study takes sex differences research to new heights
July 18, 2019
Researchers find differences in gene expression between males and females throughout the body in humans and other mammals, including ones that contribute to the average height difference between the sexes
The science of self-repair: regeneration research at Whitehead Institute
June 17, 2019
Researchers at Whitehead Institute are uncovering the underlying genetics, mechanisms, and principles of regeneration.
A troubling inheritance
April 9, 2019
Researchers have found that certain epigenetic changes in mice that appear to be inherited by offspring can lead to increased cancer rates