Whitehead Institute’s world-renowned faculty include the recipient of the 2011 National Medal of Science (Rudolf Jaenisch); 2010 National Medal of Science (Susan Lindquist); 1997 National Medal of Science (Robert A Weinberg); ten Members of the National Academy of Sciences (David Bartel, Gerald R. Fink, Jaenisch, Lindquist, Harvey F. Lodish, David Sabatini, Terry Orr-Weaver, David C. Page, Weinberg, and Richard Young); five members of the Institute of Medicine (Fink, Jaenisch, Lindquist, Page, and Weinberg); and six Fellows of the American Academy of Arts and Sciences (Fink, Jaenisch, Lindquist, Lodish, Page, and Weinberg). All Whitehead faculty are also professors at MIT.
Faculty In The News
February 2, 2017
Investigators at Whitehead Institute and the Broad Institute have succeeded in identifying the set of essential genes—those required for cellular proliferation and survival—in each of 14 human acute myeloid leukemia (AML) cell lines that had previously been characterized by genome sequencing. By combining their “gene essentiality map” with the existing genomic information, their study revealed liabilities in genetically defined subset of cancers that could be exploited for new therapies.
January 25, 2017
Parkinson’s disease (PD) and other “synucleinopathies” are known to be linked to the misfolding of alpha-synuclein protein in neurons. Less clear is how this misfolding relates to the growing number of genes implicated in PD through analysis of human genetics. Two new studies from researchers affiliated with Whitehead Institute and Massachusetts Institute of Technology explain how they used a suite of novel biological and computational methods to shed light on the question.