Izabella Pena is a postdoc in Whitehead Institute Member David Sabatini’s lab investigating how toxic proteins associated with neurodegeneration are degraded in cells. We sat down with Pena to learn more about her and her experiences in and out of the lab.
Pena, who hails from Brazil, studies in Whitehead Institute Member David Sabatini's lab how cells calibrate their growth, metabolism, and proliferation based on nutrient availability
Whitehead Institute and Broad Institute researchers determine that cancer cells commonly change their energy source, creating a weakness that the drug elesclomol exploits to resensitize cancer cells to proteasome inhibitors
Monther Abu-Remaileh is a postdoc in Whitehead Institute Member David Sabatini’s lab investigating the organelles that cells use to remove waste and recycle nutrients. We sat down with Abu-Remaileh to learn more about him and his experiences in and out of the lab.
Whitehead's David Sabatini discusses mTOR, a protein connecting metabolism, nutrition, and disease and the current research in his lab investigating the mTOR pathway and its role in cancer, diabetes, and aging.
Whitehead Member David Sabatini has identified the methionine sensor in the mTOR pathway, which is a crucial metabolic pathway in cells. His work provides interesting data suggesting that the anti-aging and anti-diabetes effects of low methionine and mTOR inhibition may be connected.