Tag: Cancer

Slides of prostate cells

Preventing prostate cancer the complex way

February 2, 2009

Blocking a specific protein complex (mTORC2) prevents prostate tumor formation in mice with a deleted PTEN gene. Inhibition of this complex in normal prostate cells, however, appears to have no effect, suggesting that the protein complex may be a future target for drug development.

Image of mammosphere

Embryonic pathway delivers stem cell traits

May 15, 2008

Understanding the role of EMT in adult stem cell creation may lead toward the development of healthy stem cells for regenerative medicine and provide drug targets for cancer.

DNA methylation shown to promote development of colon tumors

December 1, 2007

A promising pathway that may lead to prevention, diagnosis and treatment of certain cancers with minimal side effects.

Green fluorescent mesenchymal stem cells in a primary tumor

Cancer cells enlist adult stem cells to promote metastasis

October 3, 2007

The conscripts secrete a protein that fosters cell movement and invasion.

MicroRNA convicted of triggering metastasis

September 26, 2007

Overabundance of a single microRNA can cause tumors to spread to distant tissues in mice.

Heat shock proteins are co-opted for cancer

September 20, 2007

A Jekyll-Hyde mechanism that both protects healthy cells and enables cancer cells could be the basis for new cancer-fighting drugs.

Normal cells transformed into cancerous ones

Newly created cancer stem cells could aid breast cancer research

August 13, 2007

After being injected with just 100 cells, mice develop tumors that metastasize.

Exposing the genetic roots of metastasis

June 12, 2007

A key gene enhances cancer cell motility and invasiveness.

MicroRNA helps prevent tumors

February 22, 2007

A microRNA directly regulates a gene implicated in human cancers.

Images of human prostate tumor cells

3D model reveals secrets of metastasis

July 10, 2006

Advanced imaging study shows that earlier techniques have missed crucial phenomena in how cancer spreads.

Graphic of RNAi and its role in testing cancer drugs

Silencing cancer

June 7, 2006

Thijn Brummelkamp accelerates genetics research with RNA interference screens.

The people behind the paper

May 25, 2006

Here's how a string of informal scientific collaborations helped to boost our knowledge of melanomas.


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