Lourido Lab

A new study from the lab of Whitehead Institute Member Sebastian Lourido uses a method called thermal profiling to determine which proteins are involved in calcium signaling, an essential process that parasites use when invading host cells.

Haley Licon is a postdoc in Whitehead Institute Member Sebastian Lourido’s lab studying how the parasite Toxoplasma gondii switches between stages during infection. We sat down with Haley to learn more about her and her experiences in and out of the lab. 

A new screening method in the parasite Toxoplasma gondii allows researchers to look beyond whether or not a gene is essential to survival and track the gene’s product through time and physical space 

Whitehead Institute Founding Member Harvey Lodish was co-recipient of the 2021 MITx Prize for Teaching and Learning in MOOCs, and Whitehead Institute Member Sebastian Lourido has been named as one of the Burroughs Wellcome Fund’s 2021 Investigators in the Pathogenesis of Infectious Disease. 

Whitehead Institute Member Sebastian Lourido’s CRISPR screen technique reveals factors in parasites’ susceptibility to antibiotics.

Whitehead Institute researchers have used thermal profiling to match a potential antiparasitic drug to its target in Toxoplasma gondii, providing insight into the parasite’s calcium signaling pathways that could help in the development of therapeutics to treat infection.

Elizabeth Boydston is a postdoc in Whitehead Institute Member Sebastian Lourido’s lab investigating the pathogen Toxoplasmsa gondii. We sat down with Boydston to learn more about her and her experiences in and out of the lab.