Tag: Young Lab

COVID-19 scientific leaders share expertise in new MIT class

September 8, 2020

A new MIT course on the Covid-19 pandemic, available to the public online, brings together top Covid-19 experts to educate students on up-to-date pandemic science.

Bridging research and medicine: Whitehead Institute’s physician-scientists

August 12, 2020

Whitehead Institute’s physician-scientists, researchers who also practice medicine, use their unusual position to act as conduits between lab and clinic.

Proteins — and labs — coming together to prevent Rett syndrome

July 22, 2020

New discoveries about the disruption of condensates in the neurodevelopmental disorder Rett syndrome provide insights into how cells compartmentalize chromosomes as well as new potential paths for therapies.

Discovery of how cancer drugs find their targets could lead to a new toolset for drug development

June 18, 2020

Researchers in Richard Young’s lab at Whitehead Institute and collaborators have discovered how certain cancer therapeutics concentrate within cells -- a finding that could change the way scientists think about drug design.

Richard Young

Whitehead Institute Member Richard Young Elected to National Academy of Medicine

October 21, 2019

Election to the NAM is considered one of the highest honors for U.S. medical practitioners, public health leaders, and biomedical researchers.  

Illustration of scientist letting genie DNA out of a pot

Looking Beyond the Gene: An Introduction

September 30, 2019

Whitehead Institute researchers are uncovering new ways that genes are regulated that upend existing paradigms of gene expression and provide important insights into health and disease. This collection of stories and multimedia explores that research.

Illustration of moths around a light

Signaling factor seeking gene

September 25, 2019

Whitehead Institute researchers have discovered that particular signaling pathways, which transmit environmental cues and effect changes in gene expression, rely on phase-separated condensates to find, occupy, and activate the right genes in each cell type

Illustration of a train on a DNA track between droplets

An emerging view of RNA transcription and splicing

August 7, 2019

Whitehead Institute scientists discover that chemical modification contributes to trafficking between non-membrane-bound compartments that control gene expression

Illustration of observatory focused on DNA constellation

Activating a new understanding of gene regulation

November 15, 2018

A previously mysterious part of transcription factors, the activation domain, plays a key role in forming phase separated "droplets" that concentrate proteins required for transcription near genes

Images of condensates and model of a condensate

Transcriptional droplets provide evidence for new model of gene control

June 21, 2018

Whitehead Institute scientists have found evidence that the apparatus that transcribes DNA into RNA is concentrated into specialized droplets, or “condensates”, at genes that control cell identity. 

Illustration of neighborhoods within DNA loops

New study prompts rethinking transcription factor’s role in control of gene expression

December 7, 2017

Like proteins, genomes must fold appropriately to function properly; some transcription factors provide the structural support

Landon Clay, Lavinia Clay, and Charles Ellis in front of portrait of Edwin C. "Jack" Whitehead

In Memoriam: Landon T. Clay

July 31, 2017

The Whitehead Institute community has lost Landon Clay, a true friend and an avid supporter of the Institute’s scientific mission and research. 

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