Tag: Weinberg Lab

Image of mouse tissue with and without miR-31

RNA snippet suppresses spread of aggressive breast cancer

June 11, 2009

Low levels of a tiny RNA fragment in cells are associated with metastatic breast cancer in humans and increases the aggressive spread of breast cancer in mice, according to researchers at Whitehead Institute for Biomedical Research.

Image of mammosphere

Embryonic pathway delivers stem cell traits

May 15, 2008

Understanding the role of EMT in adult stem cell creation may lead toward the development of healthy stem cells for regenerative medicine and provide drug targets for cancer.

Green fluorescent mesenchymal stem cells in a primary tumor

Cancer cells enlist adult stem cells to promote metastasis

October 3, 2007

The conscripts secrete a protein that fosters cell movement and invasion.

MicroRNA convicted of triggering metastasis

September 26, 2007

Overabundance of a single microRNA can cause tumors to spread to distant tissues in mice.

Normal cells transformed into cancerous ones

Newly created cancer stem cells could aid breast cancer research

August 13, 2007

After being injected with just 100 cells, mice develop tumors that metastasize.

Exposing the genetic roots of metastasis

June 12, 2007

A key gene enhances cancer cell motility and invasiveness.

Weinberg to head Ludwig Center for Molecular Oncology at MIT

November 15, 2006

The new center, which will be administered through MIT’s Center for Cancer Research (CCR), will focus on the biology of cancer metastasis.

The people behind the paper

May 25, 2006

Here's how a string of informal scientific collaborations helped to boost our knowledge of melanomas.

Robert Weinberg awarded Landon-AACR Prize for Cancer Research

March 1, 2006

The prize is the largest awarded to cancer researchers by a professional society of their peers.

Researchers discover why melanoma is so malignant

September 5, 2005

Whitehead researchers discover that, unlike other cancers, melanoma is born with its metastatic engines fully revved.

Image: Tissue samples

Cancer exploits the body's wound-healing process, study finds

May 5, 2005

Scientists have known for the last decade that a link exists between wound healing and cancer. Now scientists in the lab of Whitehead Institute Member Robert Weinberg have discovered the process by which tumors hijack normal wound-healing processes and use them for their own purposes.

Images of cancer cells

New insight into cancer metastasis

June 24, 2004

Scientists know a great deal about how tumors originate and develop, but relatively little about how cancer manages to metastasize and invade distant tissues and organs.


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