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Whitehead Connects: An Evening With NASA Astronaut Kathleen Rubins

... for astronaut duty The human side of monkeypox (Paradigm Fall 2007 article p. 14) New Whitehead Fellow Kate Rubins ...

Fragile X syndrome neurons restored using CRISPR/Cas9-guided activation strategy

... off—suggesting that this method may prove to be a useful paradigm for targeting diseases caused by abnormal methylation. Research by ... of targeting the methylation on genes, and it will be a paradigm for scientists to follow this approach for other diseases,” says ...

Genetic body/brain connection identified in genomic region linked to autism

... between a brain and a body phenotype is indeed really paradigm shifting,” says Whitehead Institute Member Hazel Sive, who is also a ...

Hydrogen peroxide induces signals that link the mitochondrial respiratory chain to specific cellular pathway

... is a major discovery that goes against the established paradigm,” says Whitehead Institute Founding Member Harvey Lodish , who is ...

Activating a new understanding of gene regulation

... which they can bind — a haphazard approach. However, this paradigm is being upended as over the last few years researchers have ...

Whitehead Institute researchers win STAT's Editor's Pick award

... off — suggesting that this method may prove to be a useful paradigm for targeting diseases caused by abnormal methylation. Fragile X ...

Epigenetic rheostat helps uncover how gene regulation is inherited and maintained

... functions in the complete opposite way from the existing paradigm—unlike most genes, when a short section of this gene is methylated, ...

Toxic proteins and type 2 diabetes

... production and aggregation, Kayatekin harnessed a powerful paradigm established by his late mentor and supervisor Susan Lindquist, a ...

Genetic master controls expose cancers’ Achilles’ heel

... meanwhile is increasingly confident that this super-enhancer paradigm of gene regulation has important implications across human disease ...

Building a New Paradigm in Drug Discovery

Building a New Paradigm in Drug Discovery May 22, 2002 CAMBRIDGE, Mass. — It’s no ...

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