Cancer

Select achievements include:

Susan Lindquist

Determined that an increase in an ancient cellular program's activity is associated with poorer cancer patient prognosis

Robert A. Weinberg

Discovered a compound that kills breast cancer stem cells in mice

David Sabatini

Pinpointed a cellular pathway that prevents cancer response to dietary restriction

Robert A. Weinberg

Identified a cellular transition that may create cancer stem cells and cause metastasis

Robert A. Weinberg

Identified critical steps in the progression from healthy breast tissue to breast cancer

Robert A. Weinberg

Isolated the first tumor suppressor gene, the retinoblastoma gene, and created the first genetically defined human cancer cells

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