Tag: Stem Cells + Therapeutic Cloning

New tools for an old can of worms

November 2, 2005

"Regeneration is one of the great mysteries of biology that has puzzled developmental biologists for well over a century," says Whitehead Associate Member Peter Reddien. But that's changing quickly as researchers bring the powerhouses of modern biological analyses to studying these processes-with the hope that a better understanding of regeneration may eventually find medical applications.

Researchers offer proof-of-concept for Altered Nuclear Transfer

October 17, 2005

Scientists at Whitehead Institute for Biomedical Research have successfully demonstrated that a theoretical-and controversial-technique for generating embryonic stem cells is indeed possible, at least in mice.

Venn diagram

Researchers discover key to embryonic stem-cell potential

September 8, 2005

Researchers working with human embryonic stem cells have uncovered the process responsible for the single-most tantalizing characteristic of these cells: their ability to become just about any type of cell in the body, a trait known as pluripotency.

Photo:  Edward Kennedy and David Page

Kennedy brings stem cell quest to Whitehead

June 15, 2005

The United States should follow the lead of Massachusetts in legalizing responsible human embryonic stem cell research, Senator Edward Kennedy declared on June 2 at Whitehead.

Image: Tissue samples from chimeric mice

Researchers discover mechanism for multiplying adult stem cells

May 5, 2005

Researchers in the lab of Whitehead Institute Member Rudolf Jaenisch have discovered a mechanism that might enable scientists to multiply adult stem cells quickly and efficiently.

Life, death and stem cells

November 10, 2004

Both sides of the debate on therapeutic cloning are fighting for life and against death. It's probably the only thing they have in common.

Malignant cancer cells generate mice through cloning

August 8, 2004

Nature can reset the clock in certain types of cancer and reverse many of the elements responsible for causing malignancy, reports a research team led by Whitehead Institute Member Rudolf Jaenisch, in collaboration with Lynda Chin from Dana Farber Cancer Institute. The team demonstrated this by successfully cloning mice from an advanced melanoma cell.

Will the UN beat the ban?

July 7, 2004

For stem cell research, this was a “Who’s Who?” gathering. Those taking the stage at United Nations headquarters in New York included Whitehead Founding Member Rudolf Jaenisch; Douglas Melton of Harvard University; Roslin Institute’s Ian Wilmut, the Scottish embryologist who cloned Dolly; and Seoul National University’s Shin Yong Moon, who culled embryonic stem cells from the cloned human blastocyst earlier this year.

Scientists clone mice from olfactory cells

February 15, 2004

Many scientists believe that the further a cell is from the embryonic stem cell stage, the harder it is to make a successful clone using that cell’s genetic material. Now, researchers at Whitehead Institute for Biomedical Research have cloned mice using olfactory neurons – cells far removed from the embryonic state.

Study Identifies Potential New Source for Adult Stem Cells

November 13, 2003

In research reported in the online version of the journal Blood, Whitehead scientists report the discovery of a new blood stem cell growth factor. This discovery provides a new tool that allows researchers to multiply blood stem cells in culture for potential therapeutic use.

With Respect and Conscience

October 23, 2003

In the heated debate over human embryo stem cell research, voices become muddled and motivations misunderstood. Scientist Willy Lensch is among those speaking out in support of this research. His reasons are complex, he says, but his cause is clear.

Faulty Reprogramming Likely Culprit behind Cloning Failures, Review Finds

July 16, 2003

Faulty reprogramming of the genome is most likely the culprit behind abnormalities common in cloned animals, according to a review article in the July 17 issue of the New England Journal of Medicine.

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