Tag: Protein Function

How cells size up their growth opportunities

May 22, 2008

Improved understanding of this nutrient-sensing pathway may aid in developing therapies for cancer and diabetes.

Photo of Arabidopsis thaliana

Shocking evolution into action

February 18, 2008

One heat shock protein affects the expression of many complex traits genes, which may contribute to rapid evolutionary change.

Scanning electron microscope image of red blood cells

Human blood stem cells are multiplied 20-fold in culture

January 17, 2008

Advance offers promise for bone marrow transplants, gene therapy.

Heat shock proteins are co-opted for cancer

September 20, 2007

A Jekyll-Hyde mechanism that both protects healthy cells and enables cancer cells could be the basis for new cancer-fighting drugs.

Image of microarray

Scientists identify prion's infectious secret

May 9, 2007

Small regions within prions help them change other proteins' shapes.

Schematic showing the electron density of the herpes-specific protein m48

New drug target for herpes viruses?

March 8, 2007

Researchers have solved the complex structure of a recently discovered protein that is found in a wide range of herpes viruses.

Diagram of kinase function

A deeper look at gene control

August 17, 2006

A well-known class of proteins may fill in the dotted lines that connect signal transduction pathways to the genes they regulate.

Image of yeast cells epxressing alpha-synuclein

Researchers reverse Parkinson's symptoms in animal models

June 22, 2006

They repaired a key biological pathway, restoring normal neurological function.

Mad-cow protein aids creation of brain cells

February 13, 2006

The protein ultimately responsible for mad cow disease might be necessary for healthy brain function.

Mad-cow culprit maintains stem cells

January 30, 2006

The same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain themselves.

Novel mechanism for blood disease may lead to new drugs

December 20, 2005

Researchers have discovered an unusual mechanism underlying myeloproliferative disease.

Within the folds, outside the box

October 26, 2005

Feverishly hot climates. Dizzying alcohol and sugar binges. Heavy metals. Toxic drugs. Genetic mutations. Over the years, yeast, fruit flies, mustard plants and mice have struggled through their own versions of an extreme reality TV show in the laboratory of Whitehead Member Susan Lindquist.

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