Tag: Sabatini Lab

Whitehead’s Sabatini named “Distinguished Young Scholar” by W.M. Keck Foundation

July 13, 2005

Whitehead Associate Member David Sabatini has been chosen by the W.M. Keck Foundation as one of this year’s grant recipients under the Distinguished Young Scholars in Medical Research program.

Image: Microarry results

Array for the cell

May 25, 2005

Figuring what a gene does is hard work, but it’s vastly easier than it was a few years ago. Back then, you would laboriously isolate a single gene, tinker with it to get some inkling about its purpose, and then start speculating about how it might collaborate with other genes. Now, microarrays let researchers gather exponentially more data about gene expression.

RNAi Consortium to accelerate genetic research

March 16, 2005

Whitehead Institute has joined ten other leading biomedical organizations in an $18 million, three-year public-private consortium that will create a comprehensive library of gene inhibitors to be made available to the entire scientific community.

Researchers identify target for cancer drugs

February 14, 2005

For nearly a decade, scientists have been trying to fully understand a particular communication pathway inside of cells that contributes to many malignant brain and prostate cancers.

Faster drug screening

November 17, 2004

Finding molecules that can potentially be developed into therapies is a time-consuming, cumbersome process. Now, Whitehead scientists have developed a way to simplify the process so that a library of 5,000 molecular drug candidates can potentially be screened on a single slide.

Joon-Ho Sheen receives grant from U.S. Department of Defense

October 27, 2004

The United States Department of Defense has awarded a $296,568 grant to Joon-Ho Sheen, a postdoctoral researcher in the lab of Whitehead Institute Associate Member David Sabatini.

Protein targeted by drug developers not open and shut case

August 11, 2004

Discovery of the mTOR protein and the role it plays in cell growth, a process often linked to diseases such as cancer, was part serendipity and part good detective work. And like any good whodunit, the mTOR story wouldn’t be complete without an unexpected twist.

Postdoctoral Associate Wins Damon Runyon Fellowship Award

July 29, 2003

David Guertin, a postdoctoral associate in the Sabatini lab, received the distinguished Damon Runyon Fellowship Award from the Damon Runyon Cancer Research Foundation.

Industry Handoff Furthers Discovery

May 22, 2003

Scientist David Sabatini was studying a group of proteins that control cell growth, when he hit a roadblock. So, Sabatini did what many creative scientists do when faced with such a dilemma: He invented a new technique to solve his problem.

Illustration showing the many factors impacting the protein complex (Raptor, mTOR and GßL) that orchestrates cell growth.

Researchers Find New Piece of Cell Growth Puzzle

April 29, 2003

Spurred by the discover of a cellular pathway that helps switch cell growth on and off, new research links growth to a cell's ability to sense nutrients in its environments.

David Sabatini Appointed to Whitehead Faculty

October 1, 2002

The Whitehead Institute recently welcomed David Sabatini as its newest faculty member. Sabatini, who joined the Institute in 1997 as a Whitehead Fellow, was named an Associate Member at Whitehead and an Assistant Professor in the biology department at MIT.

Building a New Paradigm in Drug Discovery

May 22, 2002

It’s no secret that drug development is a painfully slow and expensive process—a typical new drug takes 15 years and $500 million to come to market, costing the pharmaceutical industry some $20 billion annually. That’s because finding a drug candidate and developing it into a treatment for disease is largely a matter of luck. To make drug discovery a more targeted science, we need to identify the complete set of all human proteins and develop tools to study them in parallel," says Whitehead Fellow David Sabatini, who was chosen as one of the world’s 100 Top Young Innovators by Technology Review magazine.

Pages

© Whitehead Institute for Biomedical Research              455 Main Street          Cambridge, MA 02142