Tag: Sabatini Lab

Whitehead Member David Sabatini wins HHMI appointment

May 27, 2008

Sabatini has been appointed a Howard Hughes Medical Investigator, a highly sought-after post that recognizes the nation’s top biomedical scientists.

How cells size up their growth opportunities

May 22, 2008

Improved understanding of this nutrient-sensing pathway may aid in developing therapies for cancer and diabetes.

Whitehead’s Sabatini named “Distinguished Young Scholar” by W.M. Keck Foundation

July 13, 2005

Whitehead Associate Member David Sabatini has been chosen by the W.M. Keck Foundation as one of this year’s grant recipients under the Distinguished Young Scholars in Medical Research program.

Image: Microarry results

Array for the cell

May 25, 2005

Figuring what a gene does is hard work, but it’s vastly easier than it was a few years ago. Back then, you would laboriously isolate a single gene, tinker with it to get some inkling about its purpose, and then start speculating about how it might collaborate with other genes. Now, microarrays let researchers gather exponentially more data about gene expression.

RNAi Consortium to accelerate genetic research

March 16, 2005

Whitehead Institute has joined ten other leading biomedical organizations in an $18 million, three-year public-private consortium that will create a comprehensive library of gene inhibitors to be made available to the entire scientific community.

Researchers identify target for cancer drugs

February 14, 2005

For nearly a decade, scientists have been trying to fully understand a particular communication pathway inside of cells that contributes to many malignant brain and prostate cancers.

Faster drug screening

November 17, 2004

Finding molecules that can potentially be developed into therapies is a time-consuming, cumbersome process. Now, Whitehead scientists have developed a way to simplify the process so that a library of 5,000 molecular drug candidates can potentially be screened on a single slide.

Joon-Ho Sheen receives grant from U.S. Department of Defense

October 27, 2004

The United States Department of Defense has awarded a $296,568 grant to Joon-Ho Sheen, a postdoctoral researcher in the lab of Whitehead Institute Associate Member David Sabatini.

Protein targeted by drug developers not open and shut case

August 11, 2004

Discovery of the mTOR protein and the role it plays in cell growth, a process often linked to diseases such as cancer, was part serendipity and part good detective work. And like any good whodunit, the mTOR story wouldn’t be complete without an unexpected twist.

Postdoctoral Associate Wins Damon Runyon Fellowship Award

July 29, 2003

David Guertin, a postdoctoral associate in the Sabatini lab, received the distinguished Damon Runyon Fellowship Award from the Damon Runyon Cancer Research Foundation.

Industry Handoff Furthers Discovery

May 22, 2003

Scientist David Sabatini was studying a group of proteins that control cell growth, when he hit a roadblock. So, Sabatini did what many creative scientists do when faced with such a dilemma: He invented a new technique to solve his problem.

Illustration showing the many factors impacting the protein complex (Raptor, mTOR and GßL) that orchestrates cell growth.

Researchers Find New Piece of Cell Growth Puzzle

April 29, 2003

Spurred by the discover of a cellular pathway that helps switch cell growth on and off, new research links growth to a cell's ability to sense nutrients in its environments.

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