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Research News

August 7, 2008

Putting microRNAs on the stem cell map
Short snippets of RNA called microRNAs help to keep embryonic stem cells in their stem cell state. Researchers now have discovered the gene circuitry that controls microRNAs in embryonic stem cells.

August 6, 2008

Recipe for cell reprogramming adds protein
Embryonic-like stem cells can be efficiently generated using a natural signaling molecule instead of the virally delivered cancer-causing gene c-Myc.

July 30, 2008

How short RNAs influence many proteins
The first large-scale study of the protein output of genes targeted by microRNAs confirms that each microRNA adjusts the production of many proteins, and sheds important light on how this regulation occurs.

July 17, 2008

Whitehead Member Peter Reddien selected as 2008 Keck Distinguished Young Scholar
Whitehead Member Peter Reddien has been named one of five Distinguished Young Scholars in Medical Research by the W.M. Keck Foundation.

July 10, 2008

Whitehead remembers Alex d’Arbeloff
Whitehead Director David Page shares thoughtful reflection upon the passing of Institute Board member Alex d'Arbeloff.

July 1, 2008

New technique produces genetically identical stem cells
Cells from mice created using genetically reprogrammed cells can be triggered via drug to enter an embryonic stem-cell-like state.

June 4, 2008

Whitehead Member Susan Lindquist honored with Harvard Centennial Medal
Whitehead Member Susan Lindquist has been awarded a Graduate School of Arts and Sciences (GSAS) Centennial Medal from Harvard University, given annually to graduate alumni who have made exceptional contributions to society.

May 27, 2008

Whitehead Member David Sabatini wins HHMI appointment
Sabatini has been appointed a Howard Hughes Medical Investigator, a highly sought-after post that recognizes the nation’s top biomedical scientists.

May 22, 2008

How cells size up their growth opportunities
Improved understanding of this nutrient-sensing pathway may aid in developing therapies for cancer and diabetes.

May 15, 2008

Embryonic pathway delivers stem cell traits
Understanding the role of EMT in adult stem cell creation may lead toward the development of healthy stem cells for regenerative medicine and provide drug targets for cancer.

April 17, 2008

Mature B cells reprogrammed to stem-cell-like state
Fully differentiated cells can be reprogrammed to induced pluripotent stem (IPS) cells.

April 7, 2008

Reprogrammed cells reduce Parkinson's symptoms in rats
Dopamine-producing neurons transplanted into adult rat brains treat behavioral symptoms related to low dopamine levels.

March 27, 2008

Susan Lindquist receives Otto Warburg Medal
Award recognizes contributions to understanding of neurological disease.

March 26, 2008

Harvey Lodish to chair MLSC Scientific Advisory Board
Peer review board aids the quasi-public agency that promotes life sciences in Massachusetts.

March 3, 2008

Whitehead ranks among best places for postdocs
Collaborative efforts continue to improve experience for young researchers.

February 18, 2008

Shocking evolution into action
One heat shock protein affects the expression of many complex traits genes, which may contribute to rapid evolutionary change.

February 17, 2008

Single microRNA fine-tunes innate immune response
A single microRNA, microRNA-223, in mice controls the production and activation of granulocytes, white blood cells essential for host defense against invading pathogens.

February 15, 2008

Gijsbert Grotenbreg is named NRF Research Fellow
Postdoc will receive up to $1.5 million for independent research in Singapore.

February 10, 2008

How red blood cells nuke their nuclei
In the first mechanistic study of how a red blood cell loses its nucleus, the research sheds light on one of the most essential steps in mammalian evolution.

February 5, 2008

Susan Lindquist receives Genetics Society of America Medal
The medal is given for outstanding contributions in the field of genetics during the past 15 years.

January 23, 2008

Whitehead Institute ranks among top in citations
Whitehead scientists top the list of authors with the most high-impact papers in molecular biology and genetics.

January 17, 2008

Human blood stem cells are multiplied 20-fold in culture
Advance offers promise for bone marrow transplants, gene therapy.

January 17, 2008

Whitehead Institute unveils innovative salary and benefits plan for postdoctoral scientists
New plan significantly improves salary and benefits for its postdoctoral scientists–a crucial step in addressing the needs of these promising young researchers.

2007, 2006, 2005, 2004, 2003, 2002, 2001, 2000, 1999, 1998, 1997, 1996, 1995

Last updated August 7, 2008.

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NOVA scienceNOW focuses on Whitehead's pioneering stem cell research
Whitehead Member Rudolf Jaenisch and MIT graduate student Alexander Meissner successfully extracted mouse stem cells from a genetically altered embryo-like entity that is unable to implant in a uterus.
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Video length: 8:00


Video courtesy of NOVA scienceNOW.
Photo: Two-headed planarium
Heads or tails?
Christian Petersen and Whitehead Member Peter Reddien identify a gene that regulates polarity in regenerating flatworms. [read more]

Photo: Christian Petersen
 
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