News Archive

 

"Photogram" Exhibit Shows Science and Art in Silhouette

October 2, 2003

Showcasing the similarities between science and art is one motivation behind a special photography exhibit in New York that features Whitehead Institute scientists Susan Lindquist and Eric Lander.

Software Tackles Protein Pathways

September 25, 2003

When biologists want to compare different sequences of DNA or protein, it’s as simple as plugging the information into a browser and pressing enter. Within 15 seconds, an online software tool contrasts one sequence of DNA with up to 18 million others catalogued in public databases. Now, a software tool developed by Whitehead Institute scientists promises to apply this same computational muscle to the far more intricate world of protein interaction networks, giving researchers a new view of the complexities of cellular life.

Lindquist Receives 2003 Dickson Prize in Medicine

September 25, 2003

Whitehead Director Susan L. Lindquist received the 2003 Dickson Prize in Medicine Sept. 24 during Science 2003: Improving the Human Condition, a three-day showcase of research held at the University of Pittsburgh.

Whitehead Genome Center Scientists Assemble Draft Sequence of Ustilago maydis

September 23, 2003

Scientists at the Whitehead Institute/MIT Center for Genome Research (WICGR) have publicly released a high quality draft genome sequence of Ustilago maydis, commonly known as corn smut, an important model system for the study of plant fungal diseases. In the United States, U. maydis poses a significant economic threat to agriculture.

New Compound Library to Speed Drug Discovery

September 4, 2003

Making drugs is a difficult and costly business. Even before companies spend exorbitant amounts on clinical trials (most of which fail), they already have spent significant time and money identifying the best drug candidates for those trials. Brent Stockwell has developed a possible shortcut for this early drug-development stage.

Laboratory “Theme Park” Re-creates RNA World for Study

August 26, 2003

Rarely, if ever, are theme parks built around a biological theme – and never do such parks fit inside a test tube. Almost never. Scientist David Bartel is hard at work on what might seem an impossibility – a microscopic theme park whose motif, the origins of life, is of equal interest to both scientists and philosophers.

Researchers Piece Together Cancer Puzzle

July 31, 2003

About four years ago, a group of Whitehead researchers created the first genetically engineered human cancer cells in the lab. They infected normal cells in mice with cancer-causing genes, and waited for tumors to form. Some cells formed large tumors, but others yielded only small, harmless bumps. What went wrong? they wondered. Or rather, What went right?

Postdoctoral Associate Wins Damon Runyon Fellowship Award

July 29, 2003

David Guertin, a postdoctoral associate in the Sabatini lab, received the distinguished Damon Runyon Fellowship Award from the Damon Runyon Cancer Research Foundation.

Studies Shed Light on Gene Response to Bacterial Infections

July 24, 2003

Making a medical diagnosis today often relies on symptomology, bacterial cultures, stain tests, experience – and luck. But new research by systems biologists at Whitehead aims to offer physicians new diagnostic tools by uncovering important differences in the way immune cells respond to bacteria.

Faulty Reprogramming Likely Culprit behind Cloning Failures, Review Finds

July 16, 2003

Faulty reprogramming of the genome is most likely the culprit behind abnormalities common in cloned animals, according to a review article in the July 17 issue of the New England Journal of Medicine.

Researchers Zero in on New Drug Combination Strategy

July 15, 2003

The magic-bullet approach to drug discovery has fallen short in treating the majority of human ailments. Doctors often rely instead on combination therapies that harness the power of multiple drugs. Researchers recently reported the development of the first systematic approach to screen for novel combination drugs, identifying several new pairings with significant therapeutic promise.

Philanthropists Eli & Edythe Broad of Los Angeles Give $100M to Create Institute with MIT, Harvard, and Whitehead to Fulfill Genome’s Promise for Medicine

June 19, 2003

In an unprecedented alliance, the Massachusetts Institute of Technology, Harvard University, and Whitehead Institute announced today they have joined forces with Los Angeles philanthropists Eli and Edythe L. Broad to create a new type of biomedical research institute, aimed at realizing the promise of the human genome to revolutionize clinical medicine and to make knowledge freely available to scientists around the world.

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