News Archive

 

Image of zebrafish

Genetic body/brain connection identified in genomic region linked to autism

October 6, 2017

For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes—fam57ba and doc2a—in zebrafish and certain brain and body traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes reside in the 16p11.2 region of the genome, which has been linked to multiple brain and body disorders in humans, including autism spectrum disorder, developmental delays, seizures, and obesity.

Richard Young, Maria Zuber, Kathleen "Kate" Rubins, David Page

Whitehead Connects: An Evening With NASA Astronaut Kathleen Rubins

September 15, 2017

Whitehead Connects was pleased to welcome NASA astronaut and former Whitehead Fellow Kathleen “Kate” Rubins on September 12, 2017.

AudioHelicase logo and Whitehead Member David Sabatini

AudioHelicase: The podcast of Whitehead Institute

September 12, 2017

Whitehead's David Sabatini discusses mTOR, a protein connecting metabolism, nutrition, and disease and the current research in his lab investigating the mTOR pathway and its role in cancer, diabetes, and aging.

Slide of red blood cells

Mystery solved: how thyroid hormone prods red blood cell production

September 5, 2017

For more than a century, the link between thyroid hormone and red blood cell production has remained elusive. Now, Whitehead scientists have teased about the mechanism that connects them, which could help scientists identify new therapies for specific types of anemia.

Landon Clay, Lavinia Clay, and Charles Ellis in front of portrait of Edwin C. "Jack" Whitehead

In Memoriam: Landon T. Clay

July 31, 2017

The Whitehead Institute community has lost Landon Clay, a true friend and an avid supporter of the Institute’s scientific mission and research. 

Whitehead Member David Sabatini

Whitehead Member David Sabatini awarded Dickson Prize in Medicine

July 20, 2017

The prize recognizes “an American biomedical researcher who has made significant, progressive contributions to medicine”.

Diagram of how the control of the translation of mRNAs into proteins shifts as the egg becomes an the embryo

Elegant switch controls translation in transition from egg to embryo

June 14, 2017

The transition from an egg to a developing embryo is one of life’s most remarkable transformations. Now Whitehead Institute researchers have used fruit flies to decipher how one aspect—control of the translation of messenger RNAs (mRNAs) into proteins—shifts as the egg becomes an the embryo.  This type of switch could tell scientists more about how human cells work and embryos develop.

Whitehead Member Jing-Ke Weng

Whitehead Member Jing-Ke Weng receives research grant from the Family Larsson-Rosenquist Foundation to examine herbs thought to boost mothers’ milk supply

June 8, 2017

Project will investigate the effectiveness and toxicity of four herbs widely used by breastfeeding women worldwide to promote human milk production

Rohgerry Deshycka, Harvey Lodish, Nova Pishesha

Undergraduate in Lodish lab doubly awarded for “outstanding” research

May 25, 2017

Rhogerry “Gerry” Deshycka, a graduating senior working in the lab of Whitehead Institute Founding Member Harvey Lodish, has received one of MIT’s two Randolph G. Wei Undergraduate Research Opportunities Program (UROP) awards for 2017 and MIT’s 2017 John L. Asinari Award

Growth medium based on human plasma rewires cell metabolism

April 6, 2017

Cultured human cells are the foundation for disease and drug research. Now Whitehead Institute researchers have designed a growth medium that more closely resembles the cells’ environment in the body—and demonstrated that, relative to decades-old recipes that have remained the workhorses of cell culture studies, it significantly alters the cells’ inner workings.

Whitehead Member David Sabatini

Whitehead Member David Sabatini awarded Foundation for the NIH Lurie Prize in Biomedical Sciences

April 4, 2017

Prize bestowed for discovery of the mTOR pathway’s impact on age-related diseases

Image of an invasive outgrowth of cancer cells

Biomarker identified for likely aggressive, early stage breast cancer

April 3, 2017

Whitehead Institute scientists have identified a gene that could help clinicians discern which patients have aggressive forms of early stage breast cancer, which could prevent hundreds of thousands of women from undergoing unnecessary treatment and save millions of dollars.

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