News Archive

 

From Seashells to Nanocomputers

December 12, 2002

What can a humble seashell tell us about how to build biocomputers at the nanoscale level—50,000 times smaller than the width of a human hair? Plenty, according to Angela M. Belcher, Professor of Materials Science and Engineering and Bioengineering at the Massachusetts Institute of Technology.

The Mouse Genome and the Measure of Man

December 4, 2002

The Whitehead Institute Center for Genome Research and the International Mouse Genome Sequencing Consortium today announced the publication of the genetic blueprint of a mouse together with insights gleaned from comparing mouse and human sequences.

Vaccine Technology Homes in on Cancer

November 21, 2002

Whitehead Institute Member Richard Young's lab has discovered a unique approach to vaccine development, which is now in phase II and III human clinical trials for the cancer-causing human papilloma virus.

Whitehead Launches Affiliate Program

November 13, 2002

In today’s research arena, success requires biologists, physicians, chemists, mathematicians, and bioinformatics specialists to funnel unique expertise into shared projects. At Whitehead, interdisciplinary collaboration has fostered discoveries at the intersection of what were once disparate disciplines and has inspired the Institute to aggressively recruit diverse talent to the lab.

Ursinus to Bestow Honorary Degree on Director Susan Lindquist

November 5, 2002

Known for groundbreaking work in the study of the stress response and protein folding, Susan L. Lindquist, the Director of the Whitehead Institute for Biomedical Research, will receive an honorary degree from Ursinus College on Nov. 12, 2002.

Whitehead Genome Center Accelerates Effort to Build Haplotype Map

October 29, 2002

The Whitehead Institute Center for Genome Research is part of an international research consortium that today launched a $100 million public-private effort to build the next generation map of the human genome. Called a "haplotype map," this effort is expected to make it easier, faster, and perhaps cheaper to find genes that predispose us to common diseases such as diabetes and cancer.

Scientists Produce the Script for Life

October 24, 2002

Imagine popping a movie into the VCR or DVD player and watching a list of credits for two hours—no movie, no plot, no dialogue—just the cast. That’s the problem facing contemporary biology. The human genome project has provided researchers with a growing list of genes—basically a cast of thousands of characters, running life inside the cell. But the key to understanding life, both in health and sickness, is the script that outlines how these cellular players interact, communicate, and cue each other.

Lindquist Lab Sheds Light on How Prion Proteins Kill Neurons

October 17, 2002

Prion diseases—such as mad cow disease in cattle and Creutzfeldt-Jakob disease (CJD) in humans—have stumped scientists for decades with a complex "whodunit" complete with many suspects and a missing murder weapon. Unlike other infectious diseases that are linked to pathogens such as bacteria and viruses, these diseases have a unique and mysterious connection to a misfolded protein.

SNPs Reveal Natural Selection in Human Populations

October 10, 2002

Some people carry better genetic armor for resisting infectious disease than others. For example, many Africans have allelic variants of several different genes that provide some resistance to malaria. Geneticists would like to know whether such resistance arose through selective pressure or merely represents random mutations that remain in the population.

David Sabatini Appointed to Whitehead Faculty

October 1, 2002

The Whitehead Institute recently welcomed David Sabatini as its newest faculty member. Sabatini, who joined the Institute in 1997 as a Whitehead Fellow, was named an Associate Member at Whitehead and an Assistant Professor in the biology department at MIT.

Genome Center Director Eric Lander to Visit His Holiness the Dalai Lama

September 30, 2002

The Genome Center got in touch with its spiritual side last week when it brought together Whitehead’s Tibetian employees—the largest Tibetan workforce in Cambridge—for afternoon tea. Almost fifty members of the Whitehead Tibetan community joined Genome Center Director Eric Lander to discuss his upcoming visit with His Holiness the Dalai Lama.

Scientists Show Cloning Leads to Severe Dysregulation of Many Genes

September 11, 2002

New results from Rudolf Jaenisch’s lab at the Whitehead Institute for Biomedical Research confirmed that the cloning process jeopardizes the integrity of an animal’s whole genome. Scientists had suspected this based on studying a mere dozen genes, but the current study, which will be reported online in the Proceedings of the National Academies of Science this week, expansively surveyed 10,000 genes for abnormalities.

Pages

© Whitehead Institute for Biomedical Research              455 Main Street          Cambridge, MA 02142