News Archive

 

Study yields insights into pathogenic fungi—and beer

August 8, 2005

Chemotherapy or organ transplantation not only take a huge toll on patients, but they can compromise the immune system and leave patients vulnerable to infections from microbes such as pathogenic fungi—the fastest-growing cause of hospital-acquired infections.

New Whitehead scientist uncovers the regenerative secrets of flatworms

July 20, 2005

Chop a planarian flatworm in half and you end up with two healthy, wiggly worms. Unfortunately, not so with a lab mouse or fruit fly. Peter Reddien, who joins the Whitehead faculty as Associate Member this August after completing a postdoctoral fellowship at the University of Utah, is determined to find out why.

Whitehead’s Sabatini named “Distinguished Young Scholar” by W.M. Keck Foundation

July 13, 2005

Whitehead Associate Member David Sabatini has been chosen by the W.M. Keck Foundation as one of this year’s grant recipients under the Distinguished Young Scholars in Medical Research program.

The double life of Christopher Hug

July 6, 2005

Splitting their time between lab and clinic, Whitehead physician-scientists bring research and reassurance to patients.

Photo: David Bartel and Lubomir Nechev

Knockout punch: the promise of RNAi

June 28, 2005

Deep in your DNA, a gene has gone haywire and is driving up the production of a protein that is messing with your body. Wouldn’t it be great to sift through all your 20,000-something genes, find the offender, and swat it like a fly? Fortunately, a new technique eventually could do just that.

Image: Diagram of how insulin aids glucose absorption

Fat chance: the biology of obesity

June 22, 2005

Better understanding of fat-cell hormones will help us attack the twin epidemics of obesity and diabetes. Harvey Lodish, a Founding Whitehead Member and professor of biology at MIT, has pioneered this field.

David Bartel honored by French academy

June 15, 2005

Whitehead Institute Member David Bartel is one of two scientists to receive the annual Louis-D. Prize from the Institut de France, an organization similar in many respects to the National Academy of Sciences in the United States.

Photo:  Edward Kennedy and David Page

Kennedy brings stem cell quest to Whitehead

June 15, 2005

The United States should follow the lead of Massachusetts in legalizing responsible human embryonic stem cell research, Senator Edward Kennedy declared on June 2 at Whitehead.

Image: Diagrams of protein fibers

Unweaving amyloid fibers to solve prion puzzles

June 8, 2005

Amyloid fibers are best known as the plaque that gunks up neurons in people with neurodegenerative illnesses such as Alzheimer’s and Creutzfeldt-Jacob disease—the human analog of mad cow disease. But even though amyloids are common and implicated in a host of conditions, researchers haven’t been able to identify their precise molecular structures.

Image: Microarry results

Array for the cell

May 25, 2005

Figuring what a gene does is hard work, but it’s vastly easier than it was a few years ago. Back then, you would laboriously isolate a single gene, tinker with it to get some inkling about its purpose, and then start speculating about how it might collaborate with other genes. Now, microarrays let researchers gather exponentially more data about gene expression.

Phillip Sharp appointed to Whitehead Board of Directors

May 11, 2005

Phillip Sharp, Nobel laureate and founding director of the McGovern Institute for Brain Research at the Massachusetts Institute of Technology, has been named to the Board of Directors of Whitehead Institute for Biomedical Research.

Image: Tissue samples from chimeric mice

Researchers discover mechanism for multiplying adult stem cells

May 5, 2005

Researchers in the lab of Whitehead Institute Member Rudolf Jaenisch have discovered a mechanism that might enable scientists to multiply adult stem cells quickly and efficiently.

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