News Archive

 

AudioHelicase logo and Whitehead Member Sebastian Lourido

AudioHelicase: Whitehead’s Sebastian Lourido on Toxoplasma, malaria parasites, and global health

November 20, 2017

Whitehead Member Sebastian Lourido discusses his work uncovering how the Toxoplasma parasite causes disease and the importance of understanding parasitic infections such as toxoplasmosis and malaria in the context of global health.

Image of a cell in anaphase

Of highways, engines, and chromosomes

November 16, 2017

Whitehead researchers unravel fundamental molecular machinery that propels chromosome movement

Illustration of scientist opening a cell and looking at a molecule

Key nutrient sensor identified for cellular pathway linking nutrient availability to cell growth

November 9, 2017

Whitehead Member David Sabatini has identified the methionine sensor in the mTOR pathway, which is a crucial metabolic pathway in cells. His work provides interesting data suggesting that the anti-aging and anti-diabetes effects of low methionine and mTOR inhibition may be connected.

Image of mouse spermatocyte, which is the source of retinoic acid

Retinoic acid regulates transitions in mouse sperm production

November 7, 2017

Researchers swimming upstream in reproductive technology work now have important insights into sperm production

Image of red algae and Roland Kersten on Ventura beach

A new workflow for natural product characterization comes ashore with red algae

October 30, 2017

Whitehead Member Jing-Ke Weng uses an omics-based path for identifying and generating sesquiterpene-based therapeutics at scale.

Illustration of scientist looking at tree of life including acoel and planarian

Small worm muscles up to reveal ancient body patterning mechanism during regeneration

October 30, 2017

Whitehead Member Peter Reddien has determined that a major function of muscle in planaria and acoels--a small regenerative marine worm auspiciously located on the evolutionary tree as an outgroup to all the rest of the Bilateria--is to serve as the source of instructive positional information for instructing regeneration.

Images of the International Space Station and NASA Astronaut Kathleen "Kate" Rubins

AudioHelicase: NASA Astronaut and Former Whitehead Fellow Kathleen "Kate" Rubins

October 23, 2017

NASA Astronaut and Former Whitehead Fellow Kathleen "Kate" Rubins discusses her journey from studying pox viruses to sequencing DNA in space.

Image of a breast cancer cell

Stuck on the membrane: A pro-metastatic transcription factor’s journey from anonymity to a promising target for breast cancer therapy

October 20, 2017

Whitehead Member Piyush Gupta has identified a protein stuck in the cell membrane that plays an important role in a cellular pathway crucial for cancer metastasis. The protein is a potential new target for breast cancer therapy that targets the cancer cells' metastatic behavior. 

Illustration of scientist measuring a cell on a scale

Study reveals key molecular link in major cell growth pathway

October 19, 2017

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.  The researchers’ findings also implicate a new protein, SLC38A9, as a potential drug target in pancreatic cancer. 

Image of zebrafish

Genetic body/brain connection identified in genomic region linked to autism

October 6, 2017

For the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes—fam57ba and doc2a—in zebrafish and certain brain and body traits, such as seizures, hyperactivity, large head size, and increased fat content. Both genes reside in the 16p11.2 region of the genome, which has been linked to multiple brain and body disorders in humans, including autism spectrum disorder, developmental delays, seizures, and obesity.

Richard Young, Maria Zuber, Kathleen "Kate" Rubins, David Page

Whitehead Connects: An Evening With NASA Astronaut Kathleen Rubins

September 15, 2017

Whitehead Connects was pleased to welcome NASA astronaut and former Whitehead Fellow Kathleen “Kate” Rubins on September 12, 2017.

AudioHelicase logo and Whitehead Member David Sabatini

AudioHelicase: The podcast of Whitehead Institute

September 12, 2017

Whitehead's David Sabatini discusses mTOR, a protein connecting metabolism, nutrition, and disease and the current research in his lab investigating the mTOR pathway and its role in cancer, diabetes, and aging.

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